Tissue clearing is a technique that reduces the opacity of biological tissues to reveal features deep within a
sample while preserving their original structure.
Estimated time: 3 weeks
Cleared imaging allows easy visualization of endogenous fluorescent reporter (e.g., GFP, YFP, RFP) tagged cells
and processes of whole organs in intact 3D tissues.
Estimated time: 2~10 days
SIM imaging can observe the internal structure of tissue slices and cells at ultra-high resolution.
Estimated time: 2~7 days
Holographic imaging can collect refractive index (RI) information of structures within the cell and selectively
pseudocolor those structures to reveal cells and their organelles.
Estimated time: 7 day
MALDI MSI is a powerful tool that enables untargeted investigations into the spatial distribution of molecular species in a variety of samples. It has the capability to image many molecules, such as metabolites, lipids, peptides, proteins, and N-glycans in a single measurement without labeling.
Estimated time: 1 month ~ 2 month
