Joon-Ho Kwon
Curriculum Vitae ( Updated: Feb 25, 2022 )
IBS ( Institute for Basic Science )
Center for Cognition and Sociality
55, Expo-ro, Yuseong-gu, Daejeon, 34126 Republic of Korea
Mobile : +82-10-4189-9405
Work Email: kwonjoonho@unist.ac.kr
Feb. 2015 Chonnam National University Gwangju, Korea
Department of Biological Sciences
B.S. in Biological Sciences
Feb. 2017 Korea University Seoul, Korea
Division of Life Sciences
Thesis: Physiological interaction between copper and zinc in aspergillus fumigatus.
Advisor: Prof. Cheol-Won Yun
M.S. in Life Sciences
Mar. 2022 UNIST (Ulsan National Institute of Science and Technology) Ulsan, Korea
~ Present Department of Biomedical Engineering
Co-Advisor: Dr. C. Justin Lee, Prof. Yoon-Kyoung Cho
Ph.D. course
Master’s student, Korea University, Laboratory of Molecular Microbiology, ( Jan. 2015 ~ Dec. 2016 )
Technical Research Personnel, Seoul National University College of Medicine, Laboratory of Molecular Imaging and Therapy ( Jan. 2017 ~ Mar. 2020 )
Researcher, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Infection and Immunity Research Laboratory ( Apr. 2020 ~ Jun. 2021 )
Researcher, Institute for Basic Science (IBS), Cognitive Glioscience group, Director: Dr. C. Justin Lee’s Lab, Center for Cognition and Sociality ( Jul. 2021 ~ Feb. 2022 )
Ph.D. Student,UNIST-IBS Neuroscience scholarship ( Mar. 2022 ~ Present )
Kim, M. J., Lee, C. H., Lee, Y., Youn, H., Kang, K. W., Kwon, J. H, ... & Chung, J. K. (2019). Glucose-6-phosphatase Expression–Mediated [18 F] FDG Efflux in Murine Inflammation and Cancer Models. Molecular imaging and biology, 21(5), 917-925.
Kang, S., Seo, H., Moon, H. S., Kwon, J. H., Park, Y. S., & Yun, C. W. (2020). The Role of Zinc in Copper Homeostasis of Aspergillus fumigatus. International journal of molecular sciences, 21(20), 7665.
Joon-Ho Kwon, Cheol-Won Yun, "Physiological interaction between copper and zinc in aspergillus fumigatus", International Meeting of the Federation of Korean Microbiological Societies (2016) – poster
Month/Year Title Institution
03/2015-09/2015 BK21 PLUS Scholarship (National Funding for Life Sciences) Korea University
09/2015-09/2016 Teaching Assistant Scholarship Korea University
General mouse works ( Organ dissection, maintenance, genotyping ), Cell culture ( Fungi, Various cancer cells, primary Thyroid cancer cells ), Cloning, Transfection, Transduction, PCR, Northern blot, RT-qPCR, Western blot, Pull-down assay, Luciferase assay, Cryosection and IHC( Immunohistochemistry ), IF( immunofluorescence ), Confocal Microscopy, Tumor ( Breast, Brain ) modeling, Stereotaxic injection, Small animal imaging test ( PET/CT, IVIS ), FACS, ICP-OES.
Jiwoon Lim
Telephone: +82-10-9187-6930 |
Research Interest
Astrocyte’s role in synapse, memory, and disease
Education
Sep. 2020-present
Mar. 2013-Feb. 2019 | Integrated Course at Institute of Basic Science Principal investigator: Dr. C. Justin Lee
Bachelor of Science and Arts at Korea University First major: Life Sciences Second major: Psychology |
Research Experience
Feb. 2019 - Aug. 2019
Sep. 2017 - Sep. 2019
Dec. 2014 - June 2015 | Research Assistant at Institute of Basic Science Dr. C. Justin Lee’s laboratory Studying on reactive astrocyte, Alzheimer’s disease & storage operated calcium entry system
Internship at Korea Institute of Science and Technology Dr. C. Justin Lee’s laboratory Studying on reactive astrocyte & Alzheimer’s disease
Internship program of Korea University Prof. Bongjune Yoon’s laboratory Setting of CrisprCas9 system & learning mouse surgery and molecular work |
Publication
Chun, H., Kim, Y., Kang, Y., Im, H., Shin, J., Won, W., Lim, J., Ju, Y., Park, Y., Kim, S., Lee, J., Woo, J., Hwang, Y., Jo, S., Wetzel I., Park, J., Kim, D., Kim, D., Gwag, B., Kim, Y., & Lee, C J. (2020). Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via excessive H2O2-production. Nature Neuroscience
Kim, W., Won, S. Y., & Yoon, B. (2019). CRMP2 mediates GSK3β actions in the striatum on regulating neuronal structure and mania-like behavior. Journal of Affective Disorders, 245, 1079-1088. In acknowledgement
Chun, H., An, H., Lim, J., Woo, J., Lee, J., Ryu, H., & Lee, C. J. (2018). Astrocytic proBDNF and tonic GABA distinguish active versus reactive astrocytes in hippocampus. Experimental Neurobiology, 27(3), 155-170. |
Poster Exhibition
Lim, J.*, Chun, H.*, Won, J., Park, Y. M., & Lee, C. J. (2019). Mao-b inhibition reduces astrogliosis and transforms reactive astrocytes into active astrocytes under pathological conditions. International Brain Research Organization, Daegu, Korea of Republic |
Lim, J.*, Jee, S., Kwon J., Sa M. & Lee, C. J. (2020). Trifluoperazine (TFP) elevates intracellular Ca2+ level and maintains the open state of the store-operated calcium entry (SOCE) in astrocyte. The Korean Society for Brain and Neural Sciences, Seoul, Korea of Republic
Research Techniques
Mouse Surgery | Perfusion, stereotaxic virus injection, IP injection, oral injection, blood prep from heart, primary cell culture |
Behavior Test
| Open field test, passive avoidance test, contextual fear conditioning, radial arm maze, novel place recognition, rotarod test, tactile discrimination test |
Histology | Cryosection, IHC, controlling confocal imaging system and analyzing (Image J & IMARIS) |
Molecular Work | Genotyping, DNA prep, RNA prep, gel electrophoresis, PCR, qRT PCR |
Calcium Imaging | Calcium ion imaging with FURA-2 at astrocyte cell culture |
Electrophysiology | Cell patch and slice patch |
Microdialysis | Extracting CSF from mouse brain and analyzing endogenous molecule |
Awards, Honors, and Scholarships
Outstanding Intern Award Internship program of the University of Science and Technology
| Feb. 2018 |