Educational background
- 2016/09 ~ Present, Ph.D. candidate in
KU-KIST Graduate School of Converging Science and Technology, Korea University,
Seoul, Republic of Korea (Advisor: C. Justin, Lee)
- 2010/03 ~ 2016/08, B.E. in Biomedical
engineering, Korea University, Seoul, Republic of Korea
- 2012/05 ~ 2014/02, KATUSA soldier program
(U.S. Army Garrison Casey, South Korea)
Research Experiences
- 2014/09 ~ 2016/05, Undergraduate
internship, Prof. Sang-Hoon Lee’s iBML lab, Korea University.
Field of interest
- Targeting
astrocytes as a novel therapeutic target for treating epilepsy.
- Physiological and pathological function
of TRIM9 in astrocytes.
- Modulation of synaptic transmission by
astrocytes.
- Mechanosensitive calcium channels on
radial glial cells.
EXPERIMENTAL TECHNIQUES
- Calcium imaging, GABA imaging
- Behavior test (Passive avoidance test, Open field test, novel
object recognition and novel place recognition test)
- Electrophysiology:
Patch clamping (Cultured cell and acute brain slice), Field recording
- Molecular biology: Cloning, RT-PCR and Western blot
- Primary astrocyte culture
- ICC and IHC
- Virus injection
Publications
-Flow Shear Stress Enhances the
Proliferative Potential of Cultured Radial Glial Cells Possibly Via an Activation
of Mechanosensitive calcium channel. Park
MG, Jang H, Lee SH, Lee CJ, Exp Neurobiol 2017 Apr;26(2):71-81. (2017)
- Development of a low-cost, comprehensive
recording system for circadian rhythm behavior. Jea Kwon, Min Gu Park, Seung Eun Lee, and C. Justin Lee. Exp
Neurobiol. 2019 Feb;28(1):30-42 (2018)
- Pharmacological Dissection of Intrinsic
Optical Signal Reveals a Functional Coupling between Synaptic Activity and
Astrocytic Volume Transient. Woo J, Han YE, Koh W, Won J, Park MG, An H, Lee CJ, Exp Neurobiol 2018 Feb
27;27(1):65-75; (2018)
- Tweety-homolog (Ttyh) Family Encodes the
Pore-forming Subunits of the Swelling-dependent Volume-regulated Anion Channel
(VRACswell) in the Brain. Han YE, Kwon J, Won J, An H, Jang MW, Woo J, Lee JS, Park MG, Yoon BE, Lee SE, Hwang
EM, Jung JY, Park H, Oh SJ, Lee CJ, Exp Neurobiol. 2019 Apr;28(2):183-215
(2019)
Awards
- 2017/03 ~ Present, Global Ph.D. Fellowship
program from National Research Foundation of Korea
Contact details - +82-010-7286-9608, +91 97667-11187 ; bmridula158@ibs.re.kr
Date of Birth : 15th August 1996
Nationality : Indian
Research Interest
Astrocytes and CNS demyelination, Astrocytes in aging
Education
Mar. 2020-present
Aug 2014 - May. 2019 | Doctoral Course at IBS School, University of Science and Technology, South Korea Principal investigator: Dr. C. Justin Lee
Masters of Science (Integrated), Pune University, India Major : Biotechnology |
Research Experience
May. 2016 - Oct. 2018
May. 2017 - Jul. 2019
Dec. 2018 – Apr 2019 | Undergraduate Student Researcher at Institute of Bioinformatics and Biotechnology, Pune University Dr. Tuli Dey’s laboratory Studying on breast cancer 3-D tumour spheroids, tumour immune microenvironment and drug synergistic action
IAS-INSA-NASI Summer Research Fellow at Rajiv Gandhi Center for Biotechnology, Kerala Dr. M. R. Pillai’s laboratory A training in techniques for the monitoring of HPV vaccination studies Visiting Intern at Daegu Gyeongbuk Institute of Science and Technology, South Korea Dr. Jinsoo Seo’s laboratory Examination of pathological phenotypes in Neural Progenitor Cells with Alzheimer’s disease-associated genetic variants |
Publication
Jung, Y., Kim, Y., Bhalla, M., Lee, S., & Seo, J. (2018). Genomics: New Light on Alzheimer’s Disease Research. International journal of molecular sciences, 19(12), 3771. |
Research Techniques
Mouse Surgery | Stereotaxic virus injection, oral injection, primary cell culture |
Animal Cell Culture techniques
| 3-D spheroid fabrication, iPS cell culture techniques |
Histology | Basic immunostaining and confocal imaging techniques, Lattice SIM imagine |
Molecular Work | Genotyping, DNA prep, RNA prep, qRT PCR, microbial transformation, enzymatic assays, ELISA, Luminex and multiplex PCR, protein purification and analysis |
Imaging | Calcium ion imaging with FURA-2 at astrocyte cell culture, Intrinsic Optical Signal Imaging, Potassium ion imaging in primary cultured astrocytes using APG1 |
Electrophysiology | Cell patch and slice patch, sniffer patch for detection of released GABA |
Awards, Honors, and Scholarships
IAS-INSA-NASI Summer Research Fellowship, 2017 |
Curricular and Extracurricular experience
Participated in the National Symposium on “Recent Trends in Epigenetics” at Pune University (2016). Attended the “One Day Symposium on Biosafety” at Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram (2017). Attended the “One Day Satellite Symposium on Neuroscience” (sponsored by the IBRO-APRC-Associate School of Neuroscience) at Pune University (2018). Chairperson of the Indo-Korean Culture Group, Pune (August 2018 – September 2019) Content writer at WittyPen (November 2015 – March 2017) |