CENTER for GENOME ENGINEERING

Publication Date 2022-11

Integration of single-cell transcriptomes and biological function reveals distinct behavioral patterns in bone marrow endothelium

Young Woong Kim,Zara, Greta,Kang, HyunJun,Branciamore, Sergio,O’Meally, Denis,Feng, Yuxin,Kuan, Chia-Yi,Luo, Yingjun,Nelson, Michael S.,Brummer, Alex B.,Rockne, Russell,Chen, Zhen Bouman,Zheng, Yi,Cardoso, Angelo A.,Carlesso, Nadia

Nature Communications, v.13, no.1

Publication Date 2022-10

Sensitivity towards HDAC inhibition is associated with RTK/MAPK pathway activation in gastric cancer

Seidlitz, Therese,Schmaeche, Tim,Garcia, Fernando,Lee, Joon Ho,Qin, Nan,Kochall, Susan,Fohgrub, Juliane,Pauck, David,Rothe, Alexander,Bonkyoung Koo,Weitz, Juergen,Remke, Marc,Munoz, Javier,Stange, Daniel E.

EMBO MOLECULAR MEDICINE, v.14, no.10

Publication Date 2022-10

Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia

Ottaviano, Giorgio,Georgiadis, Christos,Gkazi, Soragia Athina,Syed, Farhatullah,Zhan, Hong,Etuk, Annie,Preece, Roland,Chu, Jan,Kubat, Agnieszka,Adams, Stuart,Veys, Paul,Vora, Ajay,Rao, Kanchan,Qasim, Waseem,James, Jesmina,Gilmour, Kimberly,Inglott, Sarah,Thomas, Rebecca,Mhaldien, Lana,Hasnain, Attia,Izotova, Natalia,Tailor, Nina,Flutter, Barry,Ahmed, Batoul,Braybrook, Toni,Pinner, Danielle,Williams, Lindsey,Ko, Ka-Yuk,Taylor, Anna,Eshilokun, Adebimpe,Staddon, Susan,Amrolia, Persis,Chiesa, Robert,Lucchini, Giovanna,Lazareva, Arina,Mullanfroze, Khushnuma,Hill, Annette,Finch, Maria,Mead, Rachel,Young, Lindsey,Abbott, Christopher,Anclif, Philip,Ghorashian, Sara,Samarasinghe, Sujith,Rao, Anupama,Bartram, Jack,Pavasovic, Vesna,Cheng, Danny,Eddaoudi, Ayad,Farzaneh, Farzin,Domning, Sabine,Heimke, Rene,Gabriel, Richard,Sauer, Martin,Beier, Rita,Madeleine, Kirste,Eckert, Cornelia,Schilham, Marco Willem,Jansen-Hoogendijk, Anja Magdalena,Jin Soo Kim,Dae Sik Kim

Science Translational Medicine, v.14, no.668

Publication Date 2022-10

Enhanced mitochondrial DNA editing in mice using nuclear-exported TALE-linked deaminases and nucleases

Seonghyun Lee,Lee, Hyunji,Ga Young Baek,Eunji Namgung,Joo Min Park,Kim, Sanghun,Hong, Seongho,Jin Soo Kim

GENOME BIOLOGY, v.23, no.1

Publication Date 2022-09

Clone wars: From molecules to cell competition in intestinal stem cell homeostasis and disease

Colozza, Gabriele,So-Yeon Park,Bon-kyoung Koo

EXPERIMENTAL AND MOLECULAR MEDICINE, v.54, no.9, pp.1367 - 1378

Publication Date 2022-07

Base editing in human cells with monomeric DddA-TALE fusion deaminases

Young Gun Mok,Ji Min Lee,Eugene Chung,Jaesuk Lee,Kayeong Lim,Sung-Ik Cho,Jin-Soo Kim

Nature Communications, v.13, no.1

Publication Date 2022-07

DCLK1 promotes colorectal cancer stemness and aggressiveness via the XRCC5/COX2 axis

Kim, Jee-Heun,So Yeon Park,Jeon, So-El,Choi, Jang-Hyun,Lee, Choong-Jae,Jang, Tae-Young,Yun, Hyeon-Ji,Lee, Yuno,Kim, Pilho,Cho, Sang Hee,Lee, Ji Shin,Nam, Jeong-Seok

THERANOSTICS, v.12, no.12, pp.5258 - 5271

Publication Date 2022-07

Production of MSTN-mutated cattle without exogenous gene integration using CRISPR-Cas9

Gim, Gyeong-Min,Kwon, Dong-Hyeok,Eom, Kyeong-Hyun,Moon, JoonHo,Park, Ji-Hyun,Lee, Won-Wu,Jung, Dae-Jin,Kim, Dae-Hyun,Yi, Jun-Koo,Ha, Jae-Jung,Ka-Yeong Lim,Jin-Soo Kim,Jang, Goo

BIOTECHNOLOGY JOURNAL, v.17, no.7

Publication Date 2022-06

Identification of Novel Genes for Cell Fusion during Osteoclast Formation

Cho, Eunjin,Cheon, Seongmin,Ding, Mina,Kayeong Lim,Park, Sang-Wook,Park, Chungoo,Lee, Tae-Hoon

International Journal of Molecular Sciences, v.23, no.12

Publication Date 2022-06

Transient expression of an adenine base editor corrects the Hutchinson-Gilford progeria syndrome mutation and improves the skin phenotype in mice

Whisenant, Daniel,Kayeong Lim,Revechon, Gwladys,Yao, Haidong,Bergo, Martin O.,Machtel, Piotr,Jin-Soo Kim,Eriksson, Maria

NATURE COMMUNICATIONS, v.13, no.1