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IBS Institute for Basic Science

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Center for Study of Emerging and Re-emerging Viruses

Research

Research Objective

Isolation and characterizations of various severe acute respiratory syndrome coronavirus - 2 (SARS-CoV-2) from clinical specimens of COVID-19 patients
Isolation or securing the recent SARS-CoV-2 variant strains and characterization of their proliferation property
Evaluation of transmission characteristics of various SARS-CoV-2 viruses using experimental animal models

Research Contents

Isolation and characterizations of various severe acute respiratory syndrome coronavirus - 2 (SARS-CoV-2) from clinical specimens of COVID-19 patients

Evaluation of genetic mutation trends through SARS-CoV-2 isolation from domestic COVID-19 patients and their whole genome sequencing
Comparative analysis of proliferation characteristics of Korean SARS-CoV-2 strains using human and animal-derived cells sensitive to SARS-CoV-2 virus

Isolation or securing the recent SARS-CoV-2 variant strains and characterization of their proliferation property

Secured emerging alpha-, beta- and delta-SARS-CoV-2 variants that have recently spread worldwide and stocking filing
Characterization of replication characteristics using in vitro cell culture assay (ex; human and animal-derived cells)

Evaluation of transmission characteristics of various SARS-CoV viruses using experimental animal models

Analysis of virus titer in lung and pathological analysis in Syrian hamster infection model
Evaluation of virus titers in upper and lower respiratory tracts in ferrets and comparative analysis of ferret to ferret transmission characteristics