Virus and One Health
Research Content
Main purpose
- Virus and One Health Research Team focuses on the emergence and transmission of novel viruses within and between animals and human.
Main purposeVirome studies from animal and human
- Via culture-independent viral meta-/transcriptomics (viromes), we evaluate the diversity, distribution, and frequency of novel virus(es)
- By employing various phylogenetic tools (e.g., BEAST), the evolution of zoonotic virus(es) is evaluated to infer viral transmission among hosts at multiple timescales.
- All of these improves the capacity to detect, diagnose, and discover viruses that potentially pose threats to human population.
Mechanism study for viral transmission and pathogenesis in animal model systems
- To study the pathogenesis of novel virus(es), single-cell RNA sequencing technology (plus spatial genomics, e.g., AKOYA system) is used in various animal models.
- Such cutting-edge bioinformatics platform enables a deeper understanding of the mechanisms about how target viruses impact new host and switch/jump host boundaries.
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