Name : Joungha Won
Country of Citizenship : Republic of Korea
Current Status : Post-Doctoral fellow, Center for Cognition and Sociality, Institute for Basic Science (IBS)
E-mail : jwon@ibs.re.kr
2007. 03 ~ 2013. 02 BS, Department of Biology, Kyung Hee University
2013. 03 ~ 2021. 02 Integrated MS/Ph.D, program, Department of Biological Science, KAIST
2013. 02 ~ Ph.D. Candidate, Bio-Imaging and Optogenetics Laboratory, KAIST
(Professor Won Do Heo’s Lab)
2015. 03 ~ 2018. 10 Student Researcher, Center for Neuroscience,
Center for Glia-Neuron interaction, KIST (C. Justin Lee’s Lab)
2018.11 ~ Student Researcher, Center for Cognition and Sociality,
Cognitive Glioscience Group, IBS (C. Justin Lee’s lab)
Activity-dependent astrocytic proBDNF release in Learning and Memory
Activity-dependent and environment-dependent BDNF expression in astrocyte.
Development an optogenetic trap for reversible inhibition of vesicular release, synaptic transmission and behavior
Investigate calcium activity and its functions in astrocyte.
The function of astrocytic molecule in pathophysiological status, especially in stroke and Parkinson's disease.
Diagnostic tool development.
Imaging experiment: Confocal imaging, Live-cell imaging, Intrinsic optical signaling imaging, Super-resolution imaging, Calcium imaging, Total internal reflection fluorescence imaging, multi-photon image, etc.
Electrophysiology: whole-cell patch clamp in acute brain tissue and cultured cell, and field recording
Molecular biology: SNP analysis, cloning, qRT-PCR, diagnosis tool development, etc.
Next-Generation Sequencing (NGS)
Primary culture: primary cortical, hippocampal and spinal cord astrocyte cell culture, cortical neuron culture
Animal behavior experiment: Fear conditioning, Open field test, Novel object/place recognition test, Passive avoidance test, etc.
Histology: Immunohistochemistry, Immunocytochemistry
Optogenetics experiment: Imaging, molecular biology, and behavior experiment with optogenetic tools.
Best presentation Award, The Korean Society for Brain and Neural Sciences, 2020
Best article award of The Korean Society for Brain and Neural Sciences, The Korean Society for Brain and Neural Sciences, 2021
Best presentation Award, The Korean Society for Brain and Neural Sciences, 2021
Published
1. Joungha Won, Lee S, Park M, Kim TY, Park GM, Choi BY, Kim D, H Chnag, Heo WD, Kim V. N and Lee CJ., Development of a Laboratory-safe and Low-cost Detection Protocol for SARS-CoV-2 of the Coronavirus Disease 2019 (COVID-19)., Experimental Neurobiology Exp Neurobiol. 2020 Apr;29(2), 11 March (2020)
2. Joungha Won, Hasan Hüseyin Kazan, Jea Kwon, Myungsun Park, Mehmet Ali Ergun, Sureyya Ozcan, Byung Yoon Choi, Won Do Heo* and C. Justin Lee*, Ultimate COVID-19 Detection Protocol Based on Saliva Sampling and qRT-PCR with Risk Probability Assessment, Experimental Neurobiology Exp Neurobiol. 2021 Feb 28; 30(1): 13–31.
3. Chang KY, Woo D, Jung H, Lee S, Kim S, Won Joungha, Kyung T, Park H, Kim N, Yang HW, Park JY, Hwang EM, Kim D, Heo WD., Light-inducible receptor tyrosine kinases that regulate neurotrophin signalling., Nature Communications. 2014 Jun 4;5:4057. doi: 10.1038/ncomms5057.
4. Kwon J, An H, Sa M, Joungha Won, Shin JI, Lee CJ., Orai1 and Orai3 in Combination with Stim1 Mediate the Majority of Store-operated Calcium Entry in Astrocyte., Exp Neurobiol 2017 Feb;26(1):42-54. (2017)
5. Woo DH, Bae JY, Nam MH, An H, Ju YH, Joungha Won, Choi JH, Hwang EM, Han KS, Bae YC, Lee CJ, Activation of Astrocytic μ-opioid Receptor Elicits Fast Glutamate Release Through TREK-1-Containing K2P Channel in Hippocampal Astrocytes., Front Cell Neurosci. 2018 Sep 27;12:319. (2018)
6. Woo J, Han YE, Koh W, Joungha Won, Park MG, An H, Lee CJ., Pharmacological Dissection of Intrinsic Optical Signal Reveals a Functional Coupling between Synaptic Activity and Astrocytic Volume Transient., Exp Neurobiol. 2019 Feb;28(1):30-42 (2019)
7. Han YE, Kwon J, Joungha Won, An H, Jang MW, Woo J, Lee JS, Park MG, Yoon BE, Lee SE, Hwang EM, Jung JY, Park H, Oh SJ, Lee CJ., Tweety-homolog (Ttyh) Family Encodes the Pore-forming Subunits of the Swelling-dependent Volume-regulated Anion Channel (VRACswell) in the Brain., Exp Neurobiol. 2019 Apr;28(2):183-215 (2019)
8. Park M, Joungha Won, Chio BY, Lee CJ., Optimization of primer sets and detection protocols for SARS-CoV-2 of coronavirus disease 2019 (COVID-19) using PCR and real-time PCR., Experimental & Molecular Medicine 52, pages963–977(2020)
9. Kim TY, Jeon S, Jang Y, Gotina Lizaveta, Joungha Won, Ju YH, Kim S, Jang MW, Won W, Park MG, Pae AN, Han S, Kim S, Lee CJ, Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome-and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion, Experimental & Molecular Medicine, 2021
Under Review/Accepted article (on 7th, Jan., 2021)
1. Joungha Won, Pankratov Y, Lee S, Kim A, Jang MW, Lee CJ*., Heo WD*., Opto-vTrap, an optogenetic trap for reversible inhibition of vesicular release, synaptic transmission and behavior., Neuron, Under review
undergraduate : 2009.03~2016.02 Korea University