Korea VirusResearch Institute

Education / Positions held

• 2025.12-current Chief Investigator, Korea Virus Research Institute, IBS
• 2024.9-current Associate Professor, KAIST, South Korea
• 2020.9-2024.8 Assistant Professor, KAIST, South Korea
• 2017.3-2020.8 Postdoctoral fellow, Wellcome Sanger Institute, United Kingdom Advisor: Prof. Sarah A. Teichmann
• 2015.9-2017.2 Postdoctoral fellow, Seoul National University, South Korea Advisor: Prof. V. Narry Kim
• 2009.3-2015.8 Ph.D. in Biological Sciences, Seoul National University, South Korea Advisor: Prof. V. Narry Kim Thesis: “Study on the mechanism of substrate recognition by Dicer”
• 2005.3-2009.2 B.S. in Biological Sciences, Seoul National University, South Korea

Research interests

Understanding how the information stored in genome can be interpreted and expressed to coordinate diverse biological phenomenon

Selected Publications

• Tak, K. Y.*, Kim, J.*, Park, M.*, …, Kim, C.#, Park, J.-E.# (2025). Quasi-spatial single-cell transcriptome based on physical properties defines early aging associated niche in liver tissue. Nature Aging
• Kim, S.*, Jeon, J. H., …, Park J.-E.#, Yeo J.# (2024). Innate responses against the mRNA component of mRNA vaccine promote cellular immunity through IFN-β at the injection site. Nature Communications, 15:7226
• Kang, J.*, Lee, J.-H.*, …, Lee, S.-H.#, Choi, J. K.#, Park J.-E.# (2024). Systematic dissection of tumor-normal single-cell ecosystems across a thousand tumors of 30 cancer types. Nature Communications, 15:4067
• Kim, S.*, Leem, G.*, ..., Kang C. M.#, Bang. S.#, Park J.-E.# (2024). Integrative analysis of spatial and single-cell transcriptome data from human pancreatic cancer reveals an intermediate cancer cell population associated with poor prognosis. Genome Medicine, 16:20.
• Kwon, J.*, Kang, J.*, ..., An H. J.#, Lee H.-O.#, Park J.-E.#, Choi, J. K.# (2023). Single-cell mapping of combinatorial target antigens for CAR switches using logic gates. Nature Biotechnology, 1-13.
• Kang, J.*, Kim, M.*, Yoon, D. Y.*, Kim, W. S., ..., Park, M., Lee, J. S., Park J.-E.#, & Kim, S.M.# (2023). AXL+ SIGLEC6+ dendritic cells in cerebrospinal fluid and brain tissues of patients with autoimmune inflammatory demyelinating disease of CNS. Clinical Immunology, 109686.
• Polański, K.*, Young, M.D.*, Miao, Z., Meyer, K.B., Teichmann, S.A.# and Park, J.-E.#, (2020). BBKNN: Fast Batch Alignment of Single Cell Transcriptomes. Bioinformatics. 36, 964-965
• Park, J.-E.*, ..., Taghon, T., Haniffa, M., Teichmann, S.A., (2020), A cell atlas of human thymic development defines T cell repertoire formation. Science 367, eaay3224
• Park, J.-E.*, Jardine, L.*, Gottgens, B., Teichmann, S.A., Haniffa, M., (2020). Prenatal development of human immunity. Science 368, 600–603.
• Efremova, M.*, Vento-Tormo, R.*, Park, J.-E.*, Teichmann, S. A. & James, K. R. Immunology in the Era of Single-Cell Technologies. (2020), Annu. Rev. Immunol. 38, 727-757
• Son, A.*, Park, J.-E.*, Kim, V.N., (2018). PARN and TOE1 Constitute a 3’ End Maturation Module for Nuclear Non-coding RNAs. Cell Reports. 23, 888–898.
• Park, J.-E.*, Yi, H.*, Kim, Y.*, Chang, H., Kim, V.N., (2016). Regulation of Poly(A) Tail and Translation during the Somatic Cell Cycle. Molecular Cell. 62, 462–471.
• Park, J.-E.*, Heo, I.*, Tian, Y., Simanshu, D.K., Chang, H., Jee, D., Patel, D.J., Kim, V.N., (2011). Dicer recognizes the 5’ end of RNA for efficient and accurate processing. Nature 475, 201–205.

Fellowships and Awards

• 2024 KAIST Impact research award
• 2023 KAIST Impact research award
• 2022 KAIST Impact research award
• 2020-2022 POSCO TJ Science Fellowship
• 2020 EMBO Advanced Fellowship
• 2017-2019 EMBO Long-term Fellowship
• 2015 Best Ph.D. Thesis Award
• 2012-2015 Fostering Core Leaders of the Future Basic Science Program
• 2005-2008 National Science & Technology Scholarship