Center for Genomic Integrity> 유전체 항상성 연구단

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Identifying DNA Repair Mechanisms to Cure Cancer and Explain Aging

Welcome to Center for Genomic Integrity The Institute for Basic Science Center for Genomic Integrity aims to be an internationally leading research center exploring the connections between formation and repair of damage to DNA, carcinogenesis and cancer therapy.

Publications

2025 Methods in molecular biology (Clifton, N.J.)

Measurement of DNA Polymerase and Microhomology-Mediated End-Joining Activities by Gel Electrophoresis and smFRET Techniques

2025 NAR Cancer

Synergistic enhancement of PARP inhibition via small molecule UNI66-mediated suppression of BRD4-dependent transcription of RAD51 and CtIP

2025 Methods in molecular biology (Clifton, N.J.)

Detection of Chromatid Break and Micronucleus Formation Induced by Low- and High-LET Irradiation

2025 Animal Cells and Systems

TRAP1 functions in the morphogenesis of the embryonic kidney

2025 Methods in molecular biology (Clifton, N.J.)

Measurement of DNA Polymerase and Microhomology-Mediated End-Joining Activities by Gel Electrophoresis and smFRET Techniques

2025 NAR Cancer

Synergistic enhancement of PARP inhibition via small molecule UNI66-mediated suppression of BRD4-dependent transcription of RAD51 and CtIP

2025 Methods in molecular biology (Clifton, N.J.)

Detection of Chromatid Break and Micronucleus Formation Induced by Low- and High-LET Irradiation

2025 Animal Cells and Systems

TRAP1 functions in the morphogenesis of the embryonic kidney

2024 Mutation Research

The RAD51 S181P mutation shortens lifespan of female mice

STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair

2024 Nature Communications

Hidden route of protein damage through oxygen-confined photooxidation

Drosulfakinin signaling encodes early-life memory for adaptive social plasticity

2023 NAR Cancer

Detection of oxaliplatin- and cisplatin-DNA lesions requires different global genome repair mechanisms that affect their clinical efficacy

2023 Scientific Reports

Convergent differentiation of multiciliated cells

2023 Experimental and Molecular Medicine

PLCγ1 in dopamine neurons critically regulates striatal dopamine release via VMAT2 and synapsin III

2023 Biomedicines

Enrichment of Deleterious Mutated Genes Involved in Ciliary Function and Histone Modification in Brain Cancer Patient-Derived Xenograft Models

TRIP13 Participates in Immediate-Early Sensing of DNA Strand Breaks and ATM Signaling Amplification through MRE11

2022 Journal of Cachexia Sarcopenia and Muscle

Pyruvate dehydrogenase kinase 4 promotes ubiquitin-proteasome system-dependent muscle atrophy

2022 PLoS Genetics

PARP1 recruits DNA translocases to restrain DNA replication and facilitate DNA repair

2022 Chemical Research in Toxicology

Recent Advances in DNA Lesion Mapping and Repair Mechanisms

Job Openings

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Closed 제2025-2회 융합과학 연구클러스터 연구직 채용공고

2025-07-07 16:00

Closed 제2025-1회 융합과학 연구클러스터 연구직군 채용공고

2025-03-31 18:00

Closed 제2024-4회 융합과학 연구클러스터 연구직 채용공고

News

“Cutting to Survive”: How Cells Remove DNA Bridges at the Last Moment image

“Cutting to Survive”: How Cells Remove DNA Bridges at the Last Moment

IBS Conference on Genomic Integrity (May 1-2, UNIST) image

IBS Conference on Genomic Integrity (May 1-2, UNIST)

IBS-Keystone Joint International Conference to Be Held from April 27 to 30 image

IBS-Keystone Joint International Conference to Be Held from April 27 to 30

Researcher Unraveling the Secrets of the Human Body… A Breakthrough in Cancer Research Through D... image

Researcher Unraveling the Secrets of the Human Body… A Breakthrough in Cancer Research Through D...

Charting a path toward overcoming glioblastoma resistance to chemotherapy image

Charting a path toward overcoming glioblastoma resistance to chemotherapy

Discovery of Key Gene Offers New Hope in Treating Chronic Myeloid Leukemia image

Discovery of Key Gene Offers New Hope in Treating Chronic Myeloid Leukemia

[Science Knowledge Encyclopedia] DNA Damage and Repair - Endless Battle Between Spear and Shield image

[Science Knowledge Encyclopedia] DNA Damage and Repair - Endless Battle Between Spear and Shield

How a Natural Compound from Sea Squirts Combats Cancer image

How a Natural Compound from Sea Squirts Combats Cancer

IBS Launches Institute for Multidisciplinary Sciences image

IBS Launches Institute for Multidisciplinary Sciences