Korea VirusResearch Institute

Self-assembling Gn head ferritin nanoparticle vaccine provides full protection from lethal challenge of Dabie bandavirus in aged ferrets

Dokyun Kim, Eunha Kim, Semi Kim, Youseung Chung, Sung-Dong Cho, Yunseo Choi, Chih-Jen Lai, Xinghong Dai, Seokmin Kang, Mi-Jeong Kwak, Inho Cha, Ziyi Liu , Younho Choi , Su-Hyung Park , Young Ki Choi , Jae U Jung [American Society for Microbiology v.14(5)(2023)]

Dabie bandavirus, nanoparticle, tick-borne pathogens, vaccine, ferret model

Development of a Universal Cloning System for Reverse Genetics of Human Enteroviruses

Won-Suk Choi, Sol Oh, Khristine Joy C. Antigua, Ju Hwan Jeong, Beom Kyu Kim, Yu Soo Yun, Da Hyeon Kang, Seong Cheol Min, Byung-Kwan Lim, Won Seop Kim, Ji-Hyuk Lee, Eung-Gook Kim, Young Ki Choi, Yun Hee Baek, Min-Suk Song* [Microbiology Spectrum 11:1(2023)]

Human Enteroviruses, whole-genome cDNA template, universal cloning system

Increased type III interferons and NK cell functions in SARS-CoV-2-infected children

Seong Dong Jeong, Hoyoung Lee, Ju Young Chang, Seong Yong Lee, Ji Eun Choi, Eunmi Yang, Hye Won Jeong, Jae-Phil Choi*, Mi Seon Han*, Eui-Cheol Shin* [Signal Transduction and Targeted Therapy 8:54(2023)]

Adaptive immunity, Innate immunity

Omicron Subvariants, Including BA.4 and BA.5, Substantially Preserve T Cell Epitopes of Ancestral SARS-CoV-2

Kyemyung Park, Seung Jin Choi, Eui-Cheol Shin* [Immune Network 22:4(2022)]

CD4+ T cell, CD8+ T cell, major histocompatibility complex, SARS-CoV-2

CD5 Suppresses IL-15-Induced Proliferation of Human Memory CD8+ T Cells by Inhibiting mTOR Pathways

Young Joon Choi, Hoyoung Lee, Jong Hoon Kim, So-Young Kim, June-Young Koh, Moa Sa, Su-Hyung Park, Eui-Cheol Shin* [Journal of immunology (Baltimore, Md. : 1950) 209:6, 1108-1117(2022)]

IL-15, memory CD8+ T cell, NK cell, CD5, mTOR pathway

Combination therapy with nirmatrelvir and molnupiravir improves the survival of SARS-CoV-2 infected mice

Ju Hwan Jeong, Santosh Chokkakula, Seong Cheol Min, Beom Kyu Kim, Won-Suk Choi, Sol Oh, Yu Soo Yun, Da Hyeon Kang, Ok-Jun Lee, Eung-Gook Kim, Jang-Hoon Choi, Joo-Yeon Lee, Young Ki Choi, Yun Hee Baek, Min-Suk Song* [Antiviral Research 208(2022)]

SARS-CoV-2, Nirmatrelvir, Remdesivir, Molnupiravir, In vivo, Combination therapy

Enhanced antibody responses in fully vaccinated individuals against pan-SARS-CoV-2 variants following Omicron breakthrough infection

Hye Won Jeong, Se-Mi Kim, Min Kyung Jung, Ji Yun Noh, Ji-Seung Yoo, Eun-Ha Kim, Young-Il Kim, Kwangmin Yu, Seung-Gyu Jang, Juryeon Gil, Mark Anthony Casel, Rollon Rare, Jeong Ho Choi, Hee-Sung Kim, Jun Hyoung Kim, Jihye Um, Chaeyoon Kim, Yeonjae Kim, Bum Sik Chin, Sungmin Jung, Jun Yong Choi, Kyoung-Ho Song, Yong-Dae Kim, Jun-Sun Park, Joon Young Song*, Eui-Cheol Shin*, Young Ki Choi* [Cell Reports Medicine 3:9(2022)]

SARS-CoV-2, recovered patient, variant of concern, Omicron BA.1, Omicron BA.2, mRNA vaccine, T-cell immune response

Inhibition of a broad range of SARS-CoV-2 variants by antiviral phytochemicals in hACE2 mice

Eun-Ha Kim, Ba Wool Lee, Byeol Ryu, Hyo Moon Cho, Se-Mi Kim, Seung-Gyu Jang, Mark Anthony B Casel, Rare Rollon, Ji-Seung Yoo, Haryoung Poo, Won Keun Oh*, Young Ki Choi* [Antiviral research 204, 105371-(2022)]

Antiviral therapy, Chlorella, Guava, Prophylactics, SARS-CoV-2, Variants