Korea VirusResearch Institute

TCR signaling via NFATc1 constrains IL-15-induced bystander activation of human memory CD8+ T cells

Hoyoung Lee, So-Young Kim, Sang-Hoon Kim, Seongju Jeong, Kyung Hwan Kim, Chang Gon Kim, June-Young Koh, Hyung-Don Kim, Ji Won Han, Hosun Yu, Wonyong Lee, Sunwoo Min, Su-Hyung Park, Hyuk Soo Eun, Eui-Cheol Shin [Immunity 58(12), 2957-2971(2025)]

Ca(2+)–calcineurin signaling; IL-15; NFATc1; TCR; bystander activation.

Co-blockade of TGFβ and PD-1 Reinvigorates Glioblastoma-Infiltrating CD8+ T Cells That Characteristically Upregulate TGFβRI Expression

A-Reum Kim; Seung Hyuck Jeon; Junsik Park; Eui-Soon Kim; Minsuk Kwon; Jihwan Yoo; Seok-Gu Kang; Su-Hyung Park; Jong Hee ChangCorresponding Author; Eui-Cheol Shin [Clinical Cancer Research 31(15)(2025)]

Patients With Mild COVID-19 Exhibit Low Functional Avidity of SARS-CoV-2 Membrane Protein-Reactive CD4+T Cells

A-Reum Kim; Koh, June-Young; Rha, Min-Seok; Jung, Jae Hyung; Ko, Jae-Hoon; Choi, Hee Kyoung; Jeon, Ji Hoon; Seok, Hyeri; Park, Dae Won; Peck, Kyong Ran; Choi, Jun Yong; Park, Su-Hyung; Choi, Won Suk; Jeong, Hye Won; Eui-Cheol Shin [Immune Network 25(2)(2025)]

COVID-19, SARS-CoV-2, CD4-positive-T-lymphocytes, Cross-reactivity; Functional avidity

Redefining the immune landscape of hepatitis A virus infection

Colasanti, Ombretta; Yu, Hosun; Lohmann, Volker; Eui-Cheol Shin [Experimental & Molecular Medicine 51(2025)]

Investigating Human Liver Tissue-Resident Memory T Cells from the Perspectives of Gastroenterologists and Hepatologists

Han, Ji Won; Eui-Cheol Shin [Gut and Liver 19(2), 161-170(2025)]

T-lymphocytes, Tissue resident T cell, Liver diseases

SARS-CoV-2 vaccine-elicited immune responses in solid organ transplant recipients

Euri Seo; Eui-Cheol Shin; Min Kyung Jung [Clinical Transplantation and Research 38(4), 247-256(2024)]

Solid organ transplant recipients, SARS-CoV-2 vaccine, Humoral immune responses, Cellular immune responses

Epigenetic scars in regulatory T cells are retained after successful treatment of chronic hepatitis C with direct-acting antivirals

Kim, So-Young; Koh, June-Young; Lee, Dong Hyeon; Kim, Hyung-Don; Choi, Seong Jin; Yun Yeong Ko; Lee, Ha Seok; Lee, Jeong Seok; Choi, In Ah; Lee, Eun Young; Jeong, Hye Won; Min Kyung Jung; Park, Su-Hyung; Park, Jun Yong; Kim, Won; Eui-Cheol Shin [Journal of Hepatology 81(5), 806-818(2024)]

Hepatitis C virus, Direct-acting antivirals, Sustained virologic response, Regulatory T cells, Epigenetics

Reply to: “Regulatory T cell dynamics during and after chronic hepatitis C treatment”

Kim, So-Young; Eui-Cheol Shin [Journal of Hepatology 81(5), e250-(2024)]