Korea VirusResearch Institute

Self-assembling Gn head ferritin nanoparticle vaccine provides full protection from lethal challenge of Dabie bandavirus in aged ferrets

Dokyun Kim, Eunha Kim, Semi Kim, Youseung Chung, Sung-Dong Cho, Yunseo Choi, Chih-Jen Lai, Xinghong Dai, Seokmin Kang, Mi-Jeong Kwak, Inho Cha, Ziyi Liu , Younho Choi , Su-Hyung Park , Young Ki Choi , Jae U Jung [American Society for Microbiology v.14(5)(2023)]

Dabie bandavirus, nanoparticle, tick-borne pathogens, vaccine, ferret model

Development of a Universal Cloning System for Reverse Genetics of Human Enteroviruses

Won-Suk Choi, Sol Oh, Khristine Joy C. Antigua, Ju Hwan Jeong, Beom Kyu Kim, Yu Soo Yun, Da Hyeon Kang, Seong Cheol Min, Byung-Kwan Lim, Won Seop Kim, Ji-Hyuk Lee, Eung-Gook Kim, Young Ki Choi, Yun Hee Baek, Min-Suk Song* [Microbiology Spectrum 11:1(2023)]

Human Enteroviruses, whole-genome cDNA template, universal cloning system

Combination therapy with nirmatrelvir and molnupiravir improves the survival of SARS-CoV-2 infected mice

Ju Hwan Jeong, Santosh Chokkakula, Seong Cheol Min, Beom Kyu Kim, Won-Suk Choi, Sol Oh, Yu Soo Yun, Da Hyeon Kang, Ok-Jun Lee, Eung-Gook Kim, Jang-Hoon Choi, Joo-Yeon Lee, Young Ki Choi, Yun Hee Baek, Min-Suk Song* [Antiviral Research 208(2022)]

SARS-CoV-2, Nirmatrelvir, Remdesivir, Molnupiravir, In vivo, Combination therapy

Enhanced antibody responses in fully vaccinated individuals against pan-SARS-CoV-2 variants following Omicron breakthrough infection

Hye Won Jeong, Se-Mi Kim, Min Kyung Jung, Ji Yun Noh, Ji-Seung Yoo, Eun-Ha Kim, Young-Il Kim, Kwangmin Yu, Seung-Gyu Jang, Juryeon Gil, Mark Anthony Casel, Rollon Rare, Jeong Ho Choi, Hee-Sung Kim, Jun Hyoung Kim, Jihye Um, Chaeyoon Kim, Yeonjae Kim, Bum Sik Chin, Sungmin Jung, Jun Yong Choi, Kyoung-Ho Song, Yong-Dae Kim, Jun-Sun Park, Joon Young Song*, Eui-Cheol Shin*, Young Ki Choi* [Cell Reports Medicine 3:9(2022)]

SARS-CoV-2, recovered patient, variant of concern, Omicron BA.1, Omicron BA.2, mRNA vaccine, T-cell immune response

Inhibition of a broad range of SARS-CoV-2 variants by antiviral phytochemicals in hACE2 mice

Eun-Ha Kim, Ba Wool Lee, Byeol Ryu, Hyo Moon Cho, Se-Mi Kim, Seung-Gyu Jang, Mark Anthony B Casel, Rare Rollon, Ji-Seung Yoo, Haryoung Poo, Won Keun Oh*, Young Ki Choi* [Antiviral research 204, 105371-(2022)]

Antiviral therapy, Chlorella, Guava, Prophylactics, SARS-CoV-2, Variants

FRET-based hACE2 receptor mimic peptide conjugated nanoprobe for simple detection of SARS-CoV-2

Byunghoon Kang, Youngjin Lee, Jaewoo Lim, Dongeun Yong, Young Ki Choi, Sun Woo Yoon, Seungbeom Seo, Soojin Jang, Seong Uk Son, Taejoon Kang, Juyeon Jung, Kyu-Sun Lee, Myung Hee Kim*, Eun-Kyung Lim* [Chemical Engineering Journal 442:1, 136143-(2022)]

COVID-19, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, hACE2 mimic peptide, hACE2

Infection Route Impacts the Pathogenesis of Severe Fever with Thrombocytopenia Syndrome Virus in Ferrets

Su-Jin Park*, Young-Il Kim, Mark Anthony Casel, Eun-Ha Kim, Se-Mi Kim, Kwang-Min Yu, Rare Rollon, Seung-Gyu Jang, Hye Won Jeong, Young Ki Choi* [Viruses 14:6(2022)]

SFTSV, aged ferret, animal model, infection routes

Methods for fighting emerging pathogens

Luiz Carlos Junior Alcantara, Lucas Amenga-Etego, Robin Andersson, Moumita Bhaumik, Young Ki Choi, Hélène Decaluwe, Jemma Geoghegan, Bart L Haagmans, Susana López, Maowia M Mukhtar, Erni Nelwan, Elias A Rahal, Kei Sato, Ella H Sklan, Yvonne Su Chuan Fang [Nature methods 19:4, 395-397(2022)]

research methods, emerging pathogens