Korea VirusResearch Institute

Multiple HA substitutions in highly pathogenic avian influenza H5Nx viruses contributed to the change in the NA subtype preference

Khristine Joy C. Antigua,Yun Hee Baek, Won-Suk Choi, Ju Hwan Jeong, Eun-Ha Kim, Sol Oh, Sun-Woo Yoon, Changil Kim, Eung-Gook Kim, So-Young Choi, Seung Kon Hong, Young Ki Choi*, Min Suk Song* [Virulence 13:1, 990-1004(2022)]

Avian influenza, clade 2.3.4, H5Nx, antigenic drift, antigenic shift, functional balance

Age-dependent pathogenic characteristics of SARS-CoV-2 infection in ferrets

Young-Il Kim, Kwang-Min Yu, June-Young Koh, Eun-Ha Kim, Se-Mi Kim, Eun Ji Kim, Mark Anthony Casel, Rare Rollon, Seung-Gyu Jang, Min-Suk Song, Su-Jin Park, Hye Won Jeong, Eung-Gook Kim, Ok-Jun Lee, Younho Choi, Shin-Ae Lee, Su-Hyung Park, Jae U Jung*, Young Ki Choi* [Nature Communications 13:21(2022)]

COVID-19, age-dependent, ferrets, pathogenesis, clinical manifestations

T cell epitopes in SARS-CoV-2 proteins are substantially conserved in the Omicron variant

Seong Jin Choi, Dong-Uk Kim, Ji Yun Noh, Sangwoo Kim, Su-Hyung Park, Hye Won Jeong, Eui-Cheol Shin* [CELLULAR & MOLECULAR IMMUNOLOGY 19:3, 447-448(2022)]

Viral infection, SARS-CoV-2

Coinfection with SARS-CoV-2 and Influenza A Virus Increases Disease Severity and Impairs Neutralizing Antibody and CD4+ T Cell Responses

Eun-Ha Kim, Thi-Quyen Nguyen, Mark Anthony B Casel, Rare Rollon, Se-Mi Kim, Young-Il Kim, Kwang-Min Yu, Seung-Gyu Jang, Jihyun Yang, Haryoung Poo, Jae U Jung, Young Ki Choi* [Journal of Virology 96:6(2022)]

SARS-CoV-2, T cell, bronchoalveolar lavage fluid, chemokine, coinfection, cytokine, hACE2 mice, immune response, influenza A virus, neutralizing antibody

Transmissibility and pathogenicity of SARS-CoV-2 variants in animal models

Young-Il Kim, Mark Anthony B Casel, Young Ki Choi* [Journal of microbiology (Seoul, Korea) 60:3, 255-267(2022)]

SARS-CoV-2, animal models, pathogenicity, transmissibility, variants

Spatial immune heterogeneity of hypoxia-induced exhausted features in high-grade glioma

A-Reum Kim, Seong Jin Choi, Junsik Park, Minsuk Kwon, Tamrin Chowdhury, Hyeon Jong Yu, Sojin Kim, Ho Kang, Kyung-Min Kim, Su-Hyung Park, Chul-Kee Park*, Eui-Cheol Shin* [OncoImmunology 11:1(2022)]

High-grade glioma, T cell, hypoxia, immune cell, tumor microenvironment

Critical role of neutralizing antibody for SARS-CoV-2 reinfection and transmission

Young-Il Kim, Se-Mi Kim, Su-Jin Park, Eun-Ha Kim, Kwang-Min Yu, Jae-Hyung Chang, Eun Ji Kim, Mark Anthony B Casel, Rare Rollon, Seung-Gyu Jang, Jihye Um, Min-Suk Song, Hye Won Jeong, Eung-Gook Kim, Yeonjae Kim, So Yeon Kim, Jun-Sun Park, Mi Sun Park, Geun-Yong Kwon, Sang Gu Yeo, Shin-Ae Lee, Youn Jung Choi, Jae U Jung, Young Ki Choi* [Emerging Microbes and Infections 10:1, 152-160(2021)]

COVID-19, SARS-CoV-2, ferret model, neutralizing antibody, reinfection

Development of a rapid fluorescent diagnostic system to detect subtype h9 influenza a virus in chicken feces

Hien Thi Tuong, Ju Hwan Jeong, Young Ki Choi, Hyun Park, Yun Hee Baek*, Seon-Ju Yeo* [International Journal of Molecular Sciences 22:16(2021)]

fecal specimen, monoclonal antibody, rapid fluorescent immunochromatographic test, subtype H9 influenza A virus