Korea VirusResearch Institute

Distinctive Dynamics and Functions of the CD4+CD25+FOXP3+ Regulatory T Cell Population in Patients with Severe and Mild COVID-19

Hee Jin Nam; Koh, J.-Y.; Jung, J.H.; Jeong, H.; Jeong, H.W.; Cheon, S.; Park, S.-H.; Kim, Y.-S.; Eui Cheol Shin [Journal of Immunology 210(11), 1687-1699(2023)]

A Rapid Method for Generating Infectious SARS-CoV-2 and Variants Using Mutagenesis and Circular Polymerase Extension Cloning

Kim, Beom Kyu; Choi, Won-Suk; Jeong, Ju Hwan; Oh, Sol; Park, Ji-Hyun; Yun, Yu Soo; Min, Seong Cheol; Kang, Da Hyeon; Kim, Eung-Gook; Ryu, Hojin; Kim, Hye Kwon; Baek, Yun Hee; Choi, Young Ki; Song, Min-Suk [Microbiology spectrum 11(2)(2023)]

Corticosteroids reduce pathologic interferon responses by downregulating STAT1 in patients with high-risk COVID-19

Jeong, Hyun-Woo; Lee, Jeong Seok; Ko, Jae-Hoon; Hong, Seunghee; Oh, Sang Taek; Choi, Seongkyun; Peck, Kyong Ran; Yang, Ji Hun; Chung, Seok; Kim, Sung-Han; Kim, Yeon-Sook; Eui-Cheol Shin [Experimental & Molecular Medicine 55(3), 653-664(2023)]

KIR+CD8+ and NKG2A+CD8+ T cells are distinct innate-like populations in humans

Choi, S.J.; Koh, J.-Y.; Rha, M.-S.; Seo, I.-H.; Hoyoung Lee; Jeong, S.; Park, S.-H.; Eui-Cheol Shin [Cell Reports 42(3)(2023)]

killer immunoglobulin-like receptor, KIR, NKG2A, innate-like T cells, CD8+ T cells, virtual memory T cells

A heterologous AZD1222 priming and BNT162b2 boosting regimen more efficiently elicits neutralizing antibodies, but not memory T cells, than the homologous BNT162b2 regimen

Yae Jee Baek; Woo-Joong Kim; Jae-Hoon Ko; Youn-Jung Lee; Jin Young Ahn; Jung Ho Kim; Ho Cheol Jang; Hye Won Jeong; Yong Chan Kim; Yoon Soo Park; Sung-Han Kim; Kyong Ran Peck; Eui Cheol Shin; Jun Yong Choi [Vaccine 41(10), 1694-1702(2023)]

SARS-CoV-2, Vaccine, Heterologous vaccination, Hybrid immunity, Neutralizing antibody, T cell

Human CD8+ T-Cell Populations That Express Natural Killer Receptors

Koh, June-Young; Kim, Dong-Uk; Moon, Bae-Hyeon; Eui-Cheol Shin [Immune Network 23(1)(2023)]

CD8-Positive T-Lymphocytes, Natural Killer Cell Receptors, CD56 Antigen, Receptors, KIR, NKG2A Receptor, NKG2C Receptor

Better understanding CD8⁺ T cells in cancer and viral infections

Hoyoung Lee; Min Kyung Jung; Noh, Ji Yun; Park, Su-Hyung; Chung, Yeonseok; Ha, Sang-Jun; Eui-Cheol Shin [NATURE IMMUNOLOGY 24(11), 1794-1796(2023)]

CD8⁺, T cell, cancer

Self-assembling Gn head ferritin nanoparticle vaccine provides full protection from lethal challenge of Dabie bandavirus in aged ferrets

Dokyun Kim, Eunha Kim, Semi Kim, Youseung Chung, Sung-Dong Cho, Yunseo Choi, Chih-Jen Lai, Xinghong Dai, Seokmin Kang, Mi-Jeong Kwak, Inho Cha, Ziyi Liu , Younho Choi , Su-Hyung Park , Young Ki Choi , Jae U Jung [American Society for Microbiology v.14(5)(2023)]

Dabie bandavirus, nanoparticle, tick-borne pathogens, vaccine, ferret model