Korea VirusResearch Institute

Corticosteroids reduce pathologic interferon responses by downregulating STAT1 in patients with high-risk COVID-19

Jeong, Hyun-Woo; Lee, Jeong Seok; Ko, Jae-Hoon; Hong, Seunghee; Oh, Sang Taek; Choi, Seongkyun; Peck, Kyong Ran; Yang, Ji Hun; Chung, Seok; Kim, Sung-Han; Kim, Yeon-Sook; Eui-Cheol Shin [Experimental & Molecular Medicine 55(3), 653-664(2023)]

KIR+CD8+ and NKG2A+CD8+ T cells are distinct innate-like populations in humans

Choi, S.J.; Koh, J.-Y.; Rha, M.-S.; Seo, I.-H.; Hoyoung Lee; Jeong, S.; Park, S.-H.; Eui-Cheol Shin [Cell Reports 42(3)(2023)]

killer immunoglobulin-like receptor, KIR, NKG2A, innate-like T cells, CD8+ T cells, virtual memory T cells

A heterologous AZD1222 priming and BNT162b2 boosting regimen more efficiently elicits neutralizing antibodies, but not memory T cells, than the homologous BNT162b2 regimen

Yae Jee Baek; Woo-Joong Kim; Jae-Hoon Ko; Youn-Jung Lee; Jin Young Ahn; Jung Ho Kim; Ho Cheol Jang; Hye Won Jeong; Yong Chan Kim; Yoon Soo Park; Sung-Han Kim; Kyong Ran Peck; Eui Cheol Shin; Jun Yong Choi [Vaccine 41(10), 1694-1702(2023)]

SARS-CoV-2, Vaccine, Heterologous vaccination, Hybrid immunity, Neutralizing antibody, T cell

Human CD8+ T-Cell Populations That Express Natural Killer Receptors

Koh, June-Young; Kim, Dong-Uk; Moon, Bae-Hyeon; Eui-Cheol Shin [Immune Network 23(1)(2023)]

CD8-Positive T-Lymphocytes, Natural Killer Cell Receptors, CD56 Antigen, Receptors, KIR, NKG2A Receptor, NKG2C Receptor

Better understanding CD8⁺ T cells in cancer and viral infections

Hoyoung Lee; Min Kyung Jung; Noh, Ji Yun; Park, Su-Hyung; Chung, Yeonseok; Ha, Sang-Jun; Eui-Cheol Shin [NATURE IMMUNOLOGY 24(11), 1794-1796(2023)]

CD8⁺, T cell, cancer

Self-assembling Gn head ferritin nanoparticle vaccine provides full protection from lethal challenge of Dabie bandavirus in aged ferrets

Dokyun Kim, Eunha Kim, Semi Kim, Youseung Chung, Sung-Dong Cho, Yunseo Choi, Chih-Jen Lai, Xinghong Dai, Seokmin Kang, Mi-Jeong Kwak, Inho Cha, Ziyi Liu , Younho Choi , Su-Hyung Park , Young Ki Choi , Jae U Jung [American Society for Microbiology v.14(5)(2023)]

Dabie bandavirus, nanoparticle, tick-borne pathogens, vaccine, ferret model

Development of a Universal Cloning System for Reverse Genetics of Human Enteroviruses

Won-Suk Choi, Sol Oh, Khristine Joy C. Antigua, Ju Hwan Jeong, Beom Kyu Kim, Yu Soo Yun, Da Hyeon Kang, Seong Cheol Min, Byung-Kwan Lim, Won Seop Kim, Ji-Hyuk Lee, Eung-Gook Kim, Young Ki Choi, Yun Hee Baek, Min-Suk Song* [Microbiology Spectrum 11:1(2023)]

Human Enteroviruses, whole-genome cDNA template, universal cloning system

Increased type III interferons and NK cell functions in SARS-CoV-2-infected children

Seong Dong Jeong, Hoyoung Lee, Ju Young Chang, Seong Yong Lee, Ji Eun Choi, Eunmi Yang, Hye Won Jeong, Jae-Phil Choi*, Mi Seon Han*, Eui-Cheol Shin* [Signal Transduction and Targeted Therapy 8:54(2023)]

Adaptive immunity, Innate immunity