Korea VirusResearch Institute

Immunomodulaton and attenuation of lethal influenza A virus infection by oral administration with KIOM-C

Eun-Ha Kim, Philippe Noriel Q Pascua, Min-Suk Song, Yun Hee Baek, Hyeok-Il Kwon, Su-Jin Park, Gyo-Jin Lim, Se Mi Kim, Arun Decano, Kwang Jin Lee, Won-Kyung Cho, Jin Yeul Ma*, Young Ki Choi [ANTIVIRAL RESEARCH 98:3, 386-393(2013)]

Herbal medicine, Oral administration, Influenza A virus, Antiviral

The frequency of CD127+ hepatitis C virus (HCV)-specific T cells but not the expression of exhaustion markers predicts the outcome of acute HCV infection

Eui-Cheol Shin, Su-Hyung Park, Michelina Nascimbeni, Marian Major, Laura Caggiari, Valli de Re, Stephen M Feinstone, Charles M Rice, Barbara Rehermann* [Journal of Virology 87:8, 4772-4777(2013)]

hepatitis C virus, T-cell

Two Distinct Functional Patterns of Hepatitis C Virus (HCV)-Specific T Cell Responses in Seronegative, Aviremic Patients

Yoon Seok Choi, Jung Eun Lee, Seung Joo Nam, Jung Tak Park, Hyon-Suk Kim, Kyu Hun Choi, Beom Seok Kim*, Eui-Cheol Shin [PLoS ONE 8:4(2013)]

hepatitis C virus, innate immune response

Early Regulation of Viral Infection Reduces Inflammation and Rescues Mx-Positive Mice from Lethal Avian Influenza Infection

Min-Suk Song, Young-Hun Cho, Su-Jin Park, Philippe Noriel Q Pascua, Yun Hee Baek, Hyeok-Il Kwon, Ok-Jun Lee, Byung-Whi Kong, Hyunggee Kim, Eui-Cheol Shin, Chul-Joong Kim, Young Ki Choi* [AMERICAN JOURNAL OF PATHOLOGY 182:4, 1308-1321(2013)]

Mx-Positive Mice, Influenza A viruses

Prokaryote-expressed M2e protein improves H9N2 influenza vaccine efficacy and protection against lethal influenza a virus in mice

Eun-Ha Kim, Jun-Han Lee, Philippe Noriel Q Pascua, Min-Suk Song, Yun-Hee Baek, Hyeok-Il Kwon, Su-Jin Park, Gyo-Jin Lim, Arun Decano, Mohammed Ye Chowdhury, Su-Kyung Seo, Man Ki Song, Chul-Joong Kim, Young-Ki Choi* [VIROLOGY JOURNAL 10(2013)]

Influenza A virus, M2e protein, Escherichia coli, Inactivated vaccine

Sublingual administration of bacteria-expressed influenza virus hemagglutinin 1 (HA1) induces protection against infection with 2009 pandemic H1N1 influenza virus

Byoung-Shik Shim, Jung-Ah Choi, Ho-Hyun Song, Sung-Moo Park, In Su Cheon, Ji-Eun Jang, Sun Je Woo, Chung Hwan Cho, Min-Suk Song, Hyemi Kim, Kyung Joo Song, Jae Myun Lee, Suhng Wook Kim, Dae Sub Song, Young Ki Choi, Jae-Ouk Kim, Huan Huu Nguyen, Dong Wook Kim, Young Yil Bahk, Cheol-Heui Yun, Man Ki Song* [JOURNAL OF MICROBIOLOGY 51:1, 130-135(2013)]

Hemagglutinin, mucosal immune response, non-glycosylation, pandemic, sublingual

TGF-β1 and hypoxia-dependent expression of MKP-1 leads tumor resistance to death receptor-mediated cell death

J Park, J Lee, W Kang, S Chang, E-C Shin, C Choi* [Cell Death and Disease 4:2(2013)]

cell death, hypoxia, mitogen-activated protein kinase, mitogen-activated protein kinase phosphatase, transforming growth factor, tumor resistance

GMP-Compliant, Large-Scale Expanded Allogeneic Natural Killer Cells Have Potent Cytolytic Activity against Cancer Cells In Vitro and In Vivo

Okjae Lim, Yuna Lee, Hyejin Chung, Jung Hyun Her, Sang Mi Kang, Mi-young Jung, Bokyung Min, Hyejin Shin, Tae Min Kim, Dae Seog Heo, Yu Kyeong Hwang*, Eui-Cheol Shin [PLoS ONE 8:1(2013)]

Cancer, NK cell expansion, Natural killer cells