Center for
Genomic Integrity

Sirt1 carboxyl-domain is an ATP-repressible domain that is transferable to other proteins

Hyeog Kang, Shinichi Oka, Duck-Yeon Lee, Junhong Park, Angel M. Aponte, Young-Sang Jung, Jacob Bitterman, Peiyong Zhai, Yi He, Harned Kooshapur, Rodolfo Ghirlando, Nico Tjandra, Sean B. Lee, Myung K. Kim, Junichi Sadoshirna, Jay H. Chung [Nature Communications   8, 15560(2017) ]

An Annulative Synthetic Strategy for Building Triphenylene Frameworks by Multiple C−H Bond Activations

Bijoy P. Mathew, Hyun Ji Yang, Joohee Kim, Jae Bin Lee, Yun-Tae Kim, Sungmin Lee, Chang Young Lee, Wonyoung Choe, Kyungjae Myung, Jang-Ung Park, Sung You Hong [Angewandte Chemie-International Edition   56, 18, 5007-5011(2017) ]

Preparation of Stable Nitrogen Mustard DNA Interstrand Cross-Link Analogs for Biochemical and Cell Biological Studies

Alejandra Castaño, Upasana Roy, Orlando D. Sch€arer [Methods in Enzymology   591, 415-431(2017) ]

Efficient copper catalysts for C[sbnd]H bond arylation under microwave heating: Direct access to multi-substituted pivanilides

Hyun Ji Yang, Bijoy P. Mathew, Dong Gun Oh, Kyungjae Myung, Ja Hun Kwak, Sung You Hong [Catalysis Communications   90, 83-86(2017) ]

Replication origin-flanking roadblocks reveal origin-licensing dynamics and altered sequence dependence

Warner MD, Azmi IF, Kang S, Zhao YD, Bell SP [Journal Of Biological Chemistry   292, 52, 21417-21430(2017) ]

Microhomology-mediated end joining induces hypermutagenesis at breakpoint junctions.

Supriya Sinha, Fuyang Li, Diana Villarreal, Jae Hoon Shim, Suhyeon Yoon, Kyungjae Myuung, Eun Yong Shim, Sang Eun Lee [PLOS Genetics   13, 4, e1006714(2017) ]

TET family dioxygenases and DNA demethylation in stem cells and cancers.

Jungeun An, Anjana Rao, Myunggon Ko [Experimental & Molecular Medicine   49, 4, e323(2017) ]

Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes

Sanjaya C. Abeysirigunawardena, Hajin Kim, Jonathan Lai, Kaushik Ragunathan, Mollie C. Rappé, Zaida Luthey-Schulten, Taekjip Ha, Sarah A. Woodson [Nature communications   8, 1, 492(2017) ]