Korea VirusResearch Institute

Inflammasome diversity: exploring novel frontiers in the innate immune response

Yu, Gyeongju; Young Ki Choi; Lee, SangJoon [Trends in Immunology 45(4), 248-258(2024)]

innate immunity, immune response, multiple inflammasome sensors, pathogen, infection, cytokines, inflammation, pyroptosis, apoptosis, necroptosis

Deciphering perivascular macrophages and microglia in the retinal ganglion cell layers

Jeon, Jehwi; Park, Yong Soo; Sang-Hoon Kim; Kong, Eunji; Kim, Jay; Yang, Jee Myung; Lee, Joo Yong; Kim, You-Me; Kim, In-Beom; Kim, Pilhan [Frontiers in Cell and Developmental Biology 12(2024)]

retinal microglia, superficial microglia, perivascular macrophage, central nervous system border-associated macrophage, CD86+ macrophage

Dynamic Responses of Circulating T Cells After Stereotactic Body Radiation Therapy for Bone Metastasis in Patients With Breast Cancer

Jeon, Seung Hyuck; Jang, Bum-Sup; Kim, Dong-Yun; Kim, Jin Ho; Eui-Cheol Shin; Kim, In Ah [International Journal of Radiation Oncology Biology Physics 118(3), 790-800(2024)]

Ruxolitinib Improves Immune-Dysregulation Features but not Epigenetic Abnormality in a Patient with STAT1 GOF

Koh, June-Young; Kim, Doo Ri; Son, Sohee; Park, Hwanhee; Kim, Kyung-Ran; Min, Sunwoo; Lee, Ha Seok; Jhun, Byung Woo; Kang, Eun-Suk; Jung, Inkyung; Kang, Ji-Man; Kim, Yae-Jean; Eui-Cheol Shin [Journal of Clinical Immunology 44(4)(2024)]

Inborn errors of immunity, STAT1 GOF, JAK inhibitor, STAT1 GOF JAK inhibitor ATAC sequencing

HA N193D substitution in the HPAI H5N1 virus alters receptor binding affinity and enhances virulence in mammalian hosts

Jang, Seung-Gyu; Young-Il Kim; Casel, Mark Anthony B.; Choi, Jeong Ho; Gil, Ju Ryeon; Rollon, Rare; Eun-Ha Kim; Se-Mi Kim; Ho Young Ji; Dong Bin Park; Hwang, Jungwon; Jae-Woo Ahn; Kim, Myung Hee; Min-Suk Song; Young Ki Choi [Emerging Microbes & Infections 13(1)(2024)]

HPAI H5N8 virus, Clade 2.3.4.4, reassortant, pathogenecity, South Korea

IL-15 in T-Cell Responses and Immunopathogenesis

Hoyoung Lee; Park, Su-Hyung; Eui-Cheol Shin [Immune Network 24(1)(2024)]

Interleukin-15, T-lymphocytes, immunopathogenesis

Omicron BA.2 breakthrough infection elicits CD8+ T cell responses recognizing the spike of later Omicron subvariants

Sang-Hoon Kim; Jihye Kim; Jung, Sungmin; Noh, Ji Yun; Kim, Jinnam; Park, Heedo; Song, Young Goo; Peck, Kyong Ran; Park, Su-Hyung; Park, Man-Seong; Ko, Jae-Hoon; Song, Joon Young; Choi, Jun Yong; Min Kyung Jung; Eui-Cheol Shin [Science immunology 9(91)(2024)]

COVID-19 Vaccination Alters NK Cell Dynamics and Transiently Reduces HBsAg Titers Among Patients With Chronic Hepatitis B

Shin, Hyunjae; Lee, Ha Seok; Noh, Ji Yun; Koh, June-Young; Kim, So-Young; Park, Jeayeon; Chung, Sung Won; Hur, Moon Haeng; Park, Min Kyung; Lee, Yun Bin; Kim, Yoon Jun; Yoon, Jung-Hwan; Ko, Jae-Hoon; Peck, Kyong Ran; Song, Joon Young; Eui-Cheol Shin; Lee, Jeong-Hoon [Immune Network 23(5)(2023)]

COVID-19 vaccines, Chronic hepatitis B, HBsAg, NK cells, NKG2A