Korea VirusResearch Institute

Methods for fighting emerging pathogens

Luiz Carlos Junior Alcantara, Lucas Amenga-Etego, Robin Andersson, Moumita Bhaumik, Young Ki Choi, Hélène Decaluwe, Jemma Geoghegan, Bart L Haagmans, Susana López, Maowia M Mukhtar, Erni Nelwan, Elias A Rahal, Kei Sato, Ella H Sklan, Yvonne Su Chuan Fang [Nature methods 19:4, 395-397(2022)]

research methods, emerging pathogens

Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8

Xin Wu, Tian Xia, Woo-Jin Shin, Kwang-Min Yu, Wooram Jung, Alexandra Herrmann, Suan-Sin Foo, Weiqiang Chen, Pengfei Zhang, Jong-Soo Lee, Haryoung Poo, Suzy A A Comhair, Lara Jehi, Young Ki Choi, Armin Ensser, Jae U Jung* [mBio 13:2(2022)]

COVID-19, inflammation, viral IL-17

Impaired antibacterial response of liver sinusoidal V gamma 9(+)V delta 2(+) T cells in patients with chronic liver disease

Min-Seok Rha, Ji Won Han, June-Young Koh, Ha Seok Lee, Jong Hoon Kim, Kyungjoo Cho, Soon Il Kim, Myoung Soo Kim, Jae Geun Lee, Su-Hyung Park, Dong Jin Joo, Jun Yong Park*, Eui-Cheol Shin* [GUT 71:3, 605-615(2022)]

bacterial translocation, chronic liver disease, gamma-delta cells, liver immunology

Multiple HA substitutions in highly pathogenic avian influenza H5Nx viruses contributed to the change in the NA subtype preference

Khristine Joy C. Antigua,Yun Hee Baek, Won-Suk Choi, Ju Hwan Jeong, Eun-Ha Kim, Sol Oh, Sun-Woo Yoon, Changil Kim, Eung-Gook Kim, So-Young Choi, Seung Kon Hong, Young Ki Choi*, Min Suk Song* [Virulence 13:1, 990-1004(2022)]

Avian influenza, clade 2.3.4, H5Nx, antigenic drift, antigenic shift, functional balance

Age-dependent pathogenic characteristics of SARS-CoV-2 infection in ferrets

Young-Il Kim, Kwang-Min Yu, June-Young Koh, Eun-Ha Kim, Se-Mi Kim, Eun Ji Kim, Mark Anthony Casel, Rare Rollon, Seung-Gyu Jang, Min-Suk Song, Su-Jin Park, Hye Won Jeong, Eung-Gook Kim, Ok-Jun Lee, Younho Choi, Shin-Ae Lee, Su-Hyung Park, Jae U Jung*, Young Ki Choi* [Nature Communications 13:21(2022)]

COVID-19, age-dependent, ferrets, pathogenesis, clinical manifestations

T cell epitopes in SARS-CoV-2 proteins are substantially conserved in the Omicron variant

Seong Jin Choi, Dong-Uk Kim, Ji Yun Noh, Sangwoo Kim, Su-Hyung Park, Hye Won Jeong, Eui-Cheol Shin* [CELLULAR & MOLECULAR IMMUNOLOGY 19:3, 447-448(2022)]

Viral infection, SARS-CoV-2

Coinfection with SARS-CoV-2 and Influenza A Virus Increases Disease Severity and Impairs Neutralizing Antibody and CD4+ T Cell Responses

Eun-Ha Kim, Thi-Quyen Nguyen, Mark Anthony B Casel, Rare Rollon, Se-Mi Kim, Young-Il Kim, Kwang-Min Yu, Seung-Gyu Jang, Jihyun Yang, Haryoung Poo, Jae U Jung, Young Ki Choi* [Journal of Virology 96:6(2022)]

SARS-CoV-2, T cell, bronchoalveolar lavage fluid, chemokine, coinfection, cytokine, hACE2 mice, immune response, influenza A virus, neutralizing antibody

Transmissibility and pathogenicity of SARS-CoV-2 variants in animal models

Young-Il Kim, Mark Anthony B Casel, Young Ki Choi* [Journal of microbiology (Seoul, Korea) 60:3, 255-267(2022)]

SARS-CoV-2, animal models, pathogenicity, transmissibility, variants