Center for
Genomic Integrity

AP2M1 Amplification Orchestrates Notch-Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients

Hansong Lee, Eun Kyoung Kim, Hee Young Ju, Chae Rin Lee, Soyul Ahn, Eun-Sun Kim, Kyungjae Myung, Won Kyu Kim, Su-Yeon Cho, Yujin Kwon, Dokyoung Kim, Yeuni Yu, Eun Jung Kwon, Hyomin Kim, Seong Ik Mun, Dong Min Lim, Kihun Kim, Hye Jin Heo, Seung Eun Baek, Sun Young Lee, Hyunsoo Cho, Eun Young Choi, Tae Sik Goh, Ninib Baryawno, Dongjun Lee, Ki Sun Jung, Keon Hee Yoo, Chang-Kyu Oh, Yun Hak Kim [Advanced Science   Early View, e14566(2025) ]

Vascularized and Perfusable Human Heart-on-a-Chip Model Recapitulates Aspects of Myocardial Ischemia and Enables Analysis of Nanomedicine Delivery

Junyoung Kim, Xuening Zhang, Richard Wang, Adrian Najer, Qiao You Lau, Ana Cammack-Najera, Jang Ah Kim, Yoo Kyung Kang, Ruoxiao Xie, Hyemin Kim, Kai Xie, Hyeonji Lim, Tae-Eun Park, Jinmyoung Joo, Molly M. Stevens [Advanced Materials   37, 41, e18909(2025) ]

Combining Multiplexed CRISPR/Cas9-Nickase and PARP Inhibitors Efficiently and Precisely Targets Cancer Cells

Soyoung Lee, Kyunghwan Kim, Hye-Jin Jeong, Subin Choi, Himchan Cheng, Dayoung Kim, Soomin Heo, Jinhee Mun, Minjong Kim, Eunjin Lee, Yoon Ji Choi, Seon-gyeong Lee, Eun A Lee, Yewon Jang, Kayeong Lim, Heon Seok Kim, Euihwan Jeong, Seung-Jae Myung, Deok-Beom Jung, Chang Sik Yu, In Ho Song, M. Ryan Corces, Joo H. Kang, Kyungjae Myung, Taejoon Kwon, Tae-Eun Park, Jinmyoung Joo, Seung Woo Cho [Therapeutic Development and Chemical Biology   85, 15, 2890-2904(2025) ]

A novel high-throughput single-molecule technique DNA curtain: Applications for DNA metabolism

Soyeong An, Youngseo Kim, Ja Yil Lee [Molecules and Cells   48, 7, 100224(2025) ]

Revolution of Biotechnology with CRISPR

Kyungjae Myung [Experimental & Molecular Medicine   57, 1353-1354(2025) ]

Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution

Steven J. Cook, Cristine A. Kalinski, Curtis M. Loer, Nadin Memar, Maryam Majeed, Sarah Rebecca Stephen, Daniel J. Bumbarger, Metta Riebesell, Barbara Conradt, Ralf Schnabel, Ralf J. Sommer, Oliver Hobert [Science   389, 6759(2025) ]

Applications of multiplexed CRISPR–Cas for genome engineering

Himchan Cheng, Euihwan Jeong, Seung Woo Cho [Experimental & Molecular Medicineges   57, 1373-1380(2025) ]

Nucleoporins cooperate with Polycomb silencers to promote transcriptional repression and repair at DNA double-strand breaks

Hongseon Song Yubin Bae, Sangin Kim, Younghoon Kee [Proceedings of the National Academy of Sciences of the United States of America   122, 22, e2415069122(2025) ]