Korea VirusResearch Institute

Evaluation of the Immune Responses to and Cross-Protective Efficacy of Eurasian H7 Avian Influenza Viruses

Hyeok-Il Kwon, Young-Il Kim, Su-Jin Park, Min-Suk Song, Eun-Ha Kim, Se Mi Kim, Young-Jae Si, In-Won Lee, Byung-Min Song, Youn-Jeong Lee, Seok Joong Yun, Wun-Jae Kim, Young Ki Choi* [JOURNAL OF VIROLOGY 91:11(2017)]

Eurasian H7 influenza virus, H7N9, cross-reactivity, vaccines

Effects of gold nanoparticle-based vaccine size on lymph node delivery and cytotoxic T-lymphocyte responses

Sukmo Kang, Sukyung Ahn, Jeewon Lee, Jin Yong Kim, Minsuk Choi, Vipul Gujrati, Hyungjun Kim, Jinjoo Kim, Eui-Cheol Shin, Sangyong Jon* [Journal of Controlled Release 256, 56-67(2017)]

Cancer therapy, Cellular immunity, Cross presentation, Gold nanoparticles, Nanoparticle vaccines

Radiation improves antitumor effect of immune checkpoint inhibitor in murine hepatocellular carcinoma model

Kyoung-Jin Kim, Ji-Hye Kim, Seo Jin Lee, Eun-Jung Lee, Eui-Cheol Shin, Jinsil Seong* [Oncotarget 8:25, 41242-41255(2017)]

anti-PD-L1, antitumor effect, combination therapy, hepatocellular carcinoma, radiation

An inactivated hand-foot-and-mouth disease vaccine using the enterovirus 71 (C4a) strain isolated from a Korean patient induces a strong immunogenic response in mice

Hyun Ju In, Heeji Lim, Jung-Ah Lee, Hye Jin Kim, Jin-Won Kim, Ji-Yeon Hyeon, Sang-Gu Yeo, June-Woo Lee, Jung Sik Yoo, Young Ki Choi, Sang-Won Lee* [PLOS ONE 12:5(2017)]

Enterovirus, Immune response

Electrical conductance change of graphene-based devices upon surface modification for detecting botulinum neurotoxin

Daehee Kim, Ho-Jong Kim, Seung-Bo Shim, Suyong Jung, Nam Hee Lee, Seung Hoon Nahm, Eui-Cheol Shin, Wan Soo Yun, Dong Han Ha [Japanese Journal of Applied Physics 556:6(2017)]

Botulinum neurotoxin, Electrical conductance change

A Novel Inhibitor IDPP Interferes with Entry and Egress of HCV by Targeting Glycoprotein E1 in a Genotype-Specific Manner

Myungeun Lee, Jaewon Yang, Eunji Jo, Ji-Young Lee, Hee-Young Kim, Ralf Bartenschlager, Eui-Cheol Shin, Yong-Soo Bae, Marc P Windisch* [Scientific Reports 7(2017)]

Hepatitis C, Target identification

Comparable Immune Function Inhibition by the Infliximab Biosimilar CT-P13: Implications for Treatment of Inflammatory Bowel Disease

Ki Jung Lim, So Jung Lee, Sunghwan Kim, Su Yeon Lee, Min Seob Lee, Yoon A Park, Eun Jin Choi, Eun Beom Lee, Hwang Keun Jun, Jong Moon Cho, SooYoung Lee, Ki Sung Kwon, Byung Pil Lim, Myung-Shin Jeon, Eui Cheol Shin, Yong Sung Choi, Ella Fudim, Orit Picard, Miri Yavzori, Shomron Ben-Horin, Shin Jae Chang [Journal of Crohn`s and Colitis 11:5, 593-602(2017)]

ADCC, CT-P13, biosimilar, biosimilarity, inflammatory bowel disease, infliximab

GRIM-19 restricts HCV replication by attenuating intracellular lipid accumulation

Jung-Hee Kim, Pil S Sung, Eun B Lee, Wonhee Hur, Dong J Park, Eui-Cheol Shin, Marc P Windisch, Seung K Yoon* [Frontiers in Microbiology 8:APR(2017)]

anti-viral host factor, hepatitis C virus, intracellular lipid accumulation, lipogenesis, viral replication