Center for
Genomic Integrity

LRRC17 Is Linked to Prognosis of Ovarian Cancer Through a p53-dependent Anti-apoptotic Function

Chang-kyu Oh, Jeong Jun Park, Mihyang Ha, Hye Jin Heo, Junho Kang, Eun Jung Kwon, Ji Wan Kang, Youngjoo Kim, Jin Mo Kang, Seung Zhoo Yoon, Yeji Ko, Dai Sik KO, Yun Hak Kim [Anticancer Research   40, 10, 5601-5609(2020) ]

Defining the mutation signatures of DNA polymerase θ in cancer genomes

Taejoo Hwang, Shelley Reh, Yerkin Dunbayev, Yi Zhong, Yoko Takata, Jianjun Shen, Kevin M. McBride, John P. Murnane, Jong Bhak, Semin Lee, Richard D. Wood, Keiichi Takata[Keiichi Takata] [NAR Cancer   2, 3(2020) ]

Bypass of DNA interstrand crosslinks by a Rev1–DNA polymerase ζ complex

Rachel Bezalel-Buch, Young K Cheun, Upasana Roy, Orlando D Schärer, Peter M Burgers [Nucleic Acids Research   48, 15, 8461-8473(2020) ]

Background-suppressed live visualization of genomic loci with an improved CRISPR system based on a split fluorophore

Narendra Chaudhary, Si-Hyeong Nho, Hayoon Cho, Narangerel Gantumur, Jae Sun Ra, Kyungjae Myung, Hajin Kim [Genome Research   30, 9, 1306-1316(2020) ]

FAM213A is linked to prognostic significance in acute myeloid leukemia through regulation of oxidative stress and myelopoiesis

Chang-Kyu Oh; Ha M.; Han M.-E.; Heo H.J.; Kyungjae Myung; Yoonsung Lee; Oh S.-O.; Kim Y.H. [Hematological Oncology   38, 3, 381-389(2020) ]

ATAD5 suppresses centrosome over-duplication by regulating UAF1 and ID1

Seong-jung Kim, Minwoo Wie, Su Hyung Park, Tae Moon Kim, Jun Hong Park, Shinseog Kim, Kyungjae Myung, Kyoo-young Lee [CELL Cycle   19, 15, 1952-1968(2020) ]

ATAD5 restricts R-loop formation through PCNA unloading and RNA helicase maintenance at the replication fork

Sangin Kim, Nalae Kang, Su Hyung Park, James Wells, Taejoo Hwang, Eunjin Ryu, Byung Gyu Kim[Byung Gyu, Kim], Sunyoung Hwang, Seong-jung Kim, Sukhyun Kang, Semin Lee, Peter Stirling, Kyungjae Myung, Kyoo-young Lee [Nucleic Acids Research   48, 13, 7218-7238(2020) ]

Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis

Yong Hwan Park, Elaine F. Remmers, Wonyong Lee, Amanda K. Ombrello, Lawton K. Chung, Zhao Shilei, Deborah L. Stone, Maya I. Ivanov, Nicole A. Loeven, Karyl S. Barron, Patrycja Hoffmann, Michele Nehrebecky, Yeliz Z. Akkaya-Ulum, Erdal Sag, Banu Balci-Peynircioglu, Ivona Aksentijevich, Ahmet Gül, Charles N. Rotimi, Hua Chen, James B. Bliska, Seza Ozen, Daniel L. Kastner, Daniel Shriner, Jae Jin Chae [Nature Immunology   21, 8, 857-867(2020) ]