Center for
Genomic Integrity

ATAD5 restricts R-loop formation through PCNA unloading and RNA helicase maintenance at the replication fork

Sangin Kim, Nalae Kang, Su Hyung Park, James Wells, Taejoo Hwang, Eunjin Ryu, Byung Gyu Kim[Byung Gyu, Kim], Sunyoung Hwang, Seong-jung Kim, Sukhyun Kang, Semin Lee, Peter Stirling, Kyungjae Myung, Kyoo-young Lee [Nucleic Acids Research   48, 13, 7218-7238(2020) ]

Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis

Yong Hwan Park, Elaine F. Remmers, Wonyong Lee, Amanda K. Ombrello, Lawton K. Chung, Zhao Shilei, Deborah L. Stone, Maya I. Ivanov, Nicole A. Loeven, Karyl S. Barron, Patrycja Hoffmann, Michele Nehrebecky, Yeliz Z. Akkaya-Ulum, Erdal Sag, Banu Balci-Peynircioglu, Ivona Aksentijevich, Ahmet Gül, Charles N. Rotimi, Hua Chen, James B. Bliska, Seza Ozen, Daniel L. Kastner, Daniel Shriner, Jae Jin Chae [Nature Immunology   21, 8, 857-867(2020) ]

High-throughput single-molecule imaging system using nanofabricated trenches and fluorescent DNA-binding proteins

Yujin Kang, Na Young Cheon, Jongjin Cha, Ayoung Kim, Hyung-il Kim, Luda Lee, Kang O. Kim, Kyubong Jo, Ja Yil Lee [Biotechnology and Bioenineering   117, 6, 1640-1648(2020) ]

Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca2+ homeostasis

EXPERIMENTAL AND MOLECULAR MEDICINE Sun Sil Choi, Sang Kwon Lee, Joong Kwan Kim, Hye-Kyung Park, Eujin Lee, Jinho Jang, Yo Han Lee, Keon Woo Khim, Ji-Min Hyun, Hye-jin Eom, Semin Lee, Byuong Heon Kang, Young Chan Chae, Kyungjae Myung, Seung-Jae Myung, Chan Young Park, Jang Hyun Choi [Experimenal and Molecular Medicine   52, 6, 940-950(2020) ]

Mutational signatures are jointly shaped by DNA damage and repair

Volkova N.V., Meier B., Gonzalez-Huici V., Bertolini S., Gonzalez S., Vohringer H., Abascal F., Martincorena I., Campbell P.J., Anton Gartner, Gerstung M. [Nature Communications   11, 1, 2169(2020) ]

Cross-linking of the DNA repair protein O6-alkylguanine DNA alkyltransferase to DNA in the presence of cisplatin

Ming X., Michaelson-Richie E.D., Arnold S. Groehler IV, Villalta P.W., Campbell C., Tretyakova N.Y. [DNA REPAIR   89, 102840(2020) ]

Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex

Eunyoung Jeong, Seong-Gyu Lee, Hyun-Suk Kim, Jihyeon Yang, Jinwoo Shin, Youngran Kim, Jihan Kim, Orlando D Schärer, Youngjin Kim, Jung-Eun Yeo, Ho Min Kim, Yunje Cho [Nucleic Acids Research   48, 6, 3328-3342(2020) ]

Alpha-tocopherol exerts protective function against the mucotoxicity of particulate matter in amphibian and human goblet cells

Hee-Sun Yang, Hyo Jung Sim, Hanna Cho, Woo Young Bang, Ha Eun Kim, Taeg Kyu Kwon, Taejoon Kwon, Tae Joo Park [Scientific Reports   10, 1, 6224(2020) ]