Center for
Genomic Integrity

Proteomic discovery of DEK and NUMA1 as new players in UV-induced DNA damage repair mechanisms

Namwoo Kim, Mihyun Kim, Eunwoo Jeong, Jung-Eun Yeo, Byung-gyu Kim, Kyungjae Myung, Orlando D. Schärer, Kyoo-young Lee [Cell Death Discovery   11, 547(2025) ]

Functional dissection of the conserved C. elegans LEM-3/ANKLE1 nuclease reveals a crucial requirement for the LEM-like and GIY-YIG domains for DNA bridge processing

Junfang Song, Peter Geary, Khadisha Salemova, John Rouse, Ye Hong, Stéphane G M Rolland, Anton Gartner [Nucleic Acids Research   53, 6(2025) ]

When DNA Repair Backfires – Trabectedin Induces DNA Breaks in Active Genes

Vakil Takhaveev, Kook Son, Visesato Mor, Hobin Yu, Emma Dillier, Nicola Zilo, Nikolai J. L. Püllen, Dmitri Ivanov, Helle D. Ulrich, Shana J. Sturia, Orlando D. Schärer [CHIMIA   79. 4; Laureates: Junior Prizes Fall Meeting 2024(2025) ]

TRAP1 functions in the morphogenesis of the embryonic kidney

Ha Eun Kim, Taejoon Kwon, Hyo Jung Sim, Tae Joo Park [Animal Cells and Systems   29, 1(2025) ]

Targeting MMR-deficient colorectal cancer with a potent small molecule UNI110

Enkhzul Amarsanaa, Jung-Min Oh, Seon Young Lee, Saikat Maiti, Sung You Hong, Kyungjae Myung [Animal Cells and Systems   29, 1(2025) ]

Liver-specific propanoate metabolism-derived 2-ethylhexanol as a novel biomarker for precise diagnosis and prognosis of hepatocellular carcinoma

Dongyong Lee, Jinhee Mun, Jihyun Lee, Chan Jang, Geumjong Song, Jonghyuk Yun, Kwangseock Kim, Taewan Kim, Seob Jeon, Jinmyoung Joo [Biomarker Research   13, 129(2025) ]

Live-Cell Imaging of the Binding between a Chemical Drug and Its Target Proteins Based on Intracellular Redistribution of the Target Proteins

Jung Me Hwang, Young-Chul Shin, Enkhzul Amasanaa, Nayoung Kim, Seok-Pyo Hong, Insung S. Choi, Young Hye Kim, Hyun-A Seong, Kyungjae Myung, Zee-Won Lee, Kyung-Bok Lee [Bioconjugate Chemistry   (2025) ]

AP2M1 Amplification Orchestrates Notch-Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients

Hansong Lee, Eun Kyoung Kim, Hee Young Ju, Chae Rin Lee, Soyul Ahn, Eun-Sun Kim, Kyungjae Myung, Won Kyu Kim, Su-Yeon Cho, Yujin Kwon, Dokyoung Kim, Yeuni Yu, Eun Jung Kwon, Hyomin Kim, Seong Ik Mun, Dong Min Lim, Kihun Kim, Hye Jin Heo, Seung Eun Baek, Sun Young Lee, Hyunsoo Cho, Eun Young Choi, Tae Sik Goh, Ninib Baryawno, Dongjun Lee, Ki Sun Jung, Keon Hee Yoo, Chang-Kyu Oh, Yun Hak Kim [Advanced Science   Early View, e14566(2025) ]