Center for
Genomic Integrity

Genome-wide RNAi screen for regulators of UPRmt in Caenorhabditis elegans mutants with defects in mitochondrial fusion

Haeussler Simon, Yeroslaviz Assa, Rolland Stéphane G., Luehr Sebastian, Lambie Eric J., Conradt Barbara [G3: Genes, Genomes, Genetics   11, 7(2021) ]

New Synthetic Analogs of Nitrogen Mustard DNA Interstrand Cross-Links and Their Use to Study Lesion Bypass by DNA Polymerases

Young K. Cheun, Arnold S. Groehler, Orlando D. Schärer [Chemical Research in Toxicology   34, 7, 1790-1799(2021) ]

NSMF promotes the replication stress-induced DNA damage response for genome maintenance

Min Kyung Ju, Kyeong Jin Shin, Joo Rak Lee, Keon Woo Khim, Eun A. Lee, Jae Sun Ra, Byung-Gyu Kim, Han-seul Jo, Jong Hyuk Yoon, Tae Moon Kim, Kyungjae Myung, Jang Hyun Choi, Hongtae Kim, Young Chan Chae [Nucleic acids research   49, 10, 5605-5622(2021) ]

A temporally resolved transcriptome for developing "Keller" explants of the Xenopus laevis dorsal marginal zone

Anneke D. Kakebeen, Robert J. Huebner, Asako Shindo, Kujin Kwon, Taejoon Kwon, Andrea E. Wills, John B. Wallingford [Developmental Dynamics   250, 5, 717-731(2021) ]

The Last Chance Saloon

Hong Ye, Zhang Hongtao, Anton Gartner [Frontiers in Cell and Developmental Biology   9(2021) ]

ERCC1 mutations impede DNA damage repair and cause liver and kidney dysfunction in patients

Apelt Katja, White Susan M., Hyun Suk Kim, Jung-Eun Yeo, Kragten Angela, Wondergem Annelotte P., Rooimans Martin A., González-Prieto Román, Wiegant Wouter W., Lunke Sebastian, Flanagan Daniel, Pantaleo Sarah, Quinlan Catherine, Hardikar Winita, van Attikum Haico, Vertegaal Alfred C O, Wilson Brian T., Wolthuis Rob M F, Orlando D. Schärer, Luijsterburg Martijn S. [Journal of Experimental Medicine   218, 3, 1-25(2021) ]

The complexity and regulation of repair of alkylation damage to nucleic acids

Tsao Ning, Schärer Orlando D., Mosammaparast Nima [Critical Revies in Biochemistry and Moleuclar Biology   56, 2, 125-136(2021) ]

PDK2 Deficiency Prevents Ovariectomy-Induced Bone Loss in Mice by Regulating the RANKL-NFATc1 Pathway During Osteoclastogenesis

Ji‐Min Lee, Min‐Ji Kim, Sun Joo Lee, Byung‐Gyu Kim, Je‐Yong Choi, Seung Mi Lee, Hye Jin Ham, Jung‐Min Koh, Jae‐Han Jeon, In‐Kyu Lee [Journal of Bone and Mineral Research   36, 3, 553-566(2021) ]