Korea VirusResearch Institute

Cross-genotype protection of live-attenuated vaccine candidate for severe fever with thrombocytopenia syndrome virus in a ferret model

Kwang-Min Yu, Su-Jin Park, Min-Ah Yu, Young-Il Kim, Younho Choi, Jae U Jung, Benjamin Brennan*, Young Ki Choi* [PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116:52, 26900-26908(2019)]

SFTS, bunyavirus, emerging banyangvirus, ferret model, live attenuated vaccine

A Novel Neuraminidase-Dependent Hemagglutinin Cleavage Mechanism Enables the Systemic Spread of an H7N6 Avian Influenza Virus

Hyeok-Il Kwon, Young-Il Kim, Su-Jin Park, Eun-Ha Kim, Semi Kim, Young-Jae Si, Min-Suk Song, Philippe Noriel Q Pascua, Elena A Govorkova, Robert G Webster, Richard J Webby*, Young Ki Choi* [MBIO 10:6(2019)]

GRG motif, H7, N6 neuraminidase, influenza, pathogenicity, thrombin-like protease, trypsin-independent growth, virulence

VEGF-A drives TOX-dependent T cell exhaustion in anti-PD-1-resistant microsatellite stable colorectal cancers

Chang Gon Kim, Mi Jang, Youngun Kim, Galam Leem, Kyung Hwan Kim, Hoyoung Lee, Tae-Shin Kim, Seong Jin Choi, Hyung-Don Kim, Ji Won Han, Minsuk Kwon, Jong Hoon Kim, Andrew J Lee, Su Kyung Nam, Seok-Joo Bae, Sat Byol Lee, Sang Joon Shin, Sung Ho Park, Joong Bae Ahn, Inkyung Jung, Kang Young Lee, Su-Hyung Park, Hoguen Kim*, Byung Soh Min*, Eui-Cheol Shin* [SCIENCE IMMUNOLOGY 4:41(2019)]

T cell exhaustion, TOX

One-Step Microfluidic Purification of White Blood Cells from Whole Blood for Immunophenotyping

Byeongyeon Kim, Kyung Hwan Kim, Yunjung Chang, Suyeon Shin, Eui-Cheol Shin*, Sungyoung Choi [Analytical Chemistry 91:20, 13230-13230(2019)]

Anatomy, Biotechnology, Fluid dynamics, Lattices, Purification

Increased frequency of CD4+CD57+ senescent T cells in patients with newly diagnosed acute heart failure: exploring new pathogenic mechanisms with clinical relevance

Jong-Chan Youn*, Min Kyung Jung, Hee Tae Yu, Ji-Soo Kwon, Jeong-Eun Kwak, Su-Hyung Park, In-Cheol Kim, Myung-Soo Park, Sun Ki Lee, Suk-Won Choi, Seongwoo Han, Kyu-Hyung Ryu, Seok-Min Kang, Eui-Cheol Shin [Scientific Reports 9:1(2019)]

Heart failure, Translational immunology

Greater Efficacy of Black Ginseng (CJ EnerG) over Red Ginseng against Lethal Influenza A Virus Infection

Eun-Ha Kim, Son-Woo Kim, Su-Jin Park, Semi Kim, Kwang-Min Yu, Seong Gyu Kim, Seung Hun Lee, Yong-Ki Seo, Nam-Hoon Cho, Kimoon Kang, Do Y Soung*, Young-Ki Choi* [NUTRIENTS 11:8(2019)]

antiviral, black ginseng, cytokines, influenza A virus, oral administration

Development of a SFTSV DNA vaccine that confers complete protection against lethal infection in ferrets

Jeong-Eun Kwak, Young-Il Kim, Su-Jin Park, Min-Ah Yu, Hyeok-Il Kwon, Sukyeong Eo, Tae-Shin Kim, Joon Seok, Won-Suk Choi, Ju Hwan Jeong, Hyojin Lee, Youngran Cho, Jin Ah Kwon, Moonsup Jeong, Joel N Maslow, Yong-Eun Kim, Haili Jeon, Kee K Kim, Eui-Cheol Shin, Min-Suk Song, Jae U Jung, Young Ki Choi*, Su-Hyung Park* [NATURE COMMUNICATIONS 10:1(2019)]

DNA vaccines, Viral infection

Rapid and simple colorimetric detection of multiple influenza viruses infecting humans using a reverse transcriptional loop-mediated isothermal amplification (RT-LAMP) diagnostic platform

Su Jeong Ahn, Yun Hee Baek, Khristine Kaith S Lloren, Won-Suk Choi, Ju Hwan Jeong, Khristine Joy C Antigua, Hyeok-Il Kwon, Su-Jin Park, Eun-Ha Kim, Young-Il Kim, Young-Jae Si, Seung Bok Hong, Kyeong Seob Shin, Sungkun Chun, Young Ki Choi*, Min-Suk Song* [BMC INFECTIOUS DISEASES 19(2019)]

Cohort studies, Republic of Korea, adult, cardiovascular diseases, metabolic diseases