Center for
Genomic Integrity

Single-molecule fluorescence imaging techniques reveal molecular mechanisms underlying deoxyribonucleic acid damage repair

Kang Yujin, An Soyeong, Min Duyoung, Ja Yil Lee [Frontiers in Bioengineering and Biotechnology   10(2022) ]

Adaptive cellular response of the substantia nigra dopaminergic neurons upon age-dependent iron accumulation

Kwon Kujin, Cho Hwapyeong, Lee Soyeon, Cho Eun Jeong, Yu Weonjin, Kok Catherine Yen Li, Je Hyunsoo Shawn, Kim Jae-Ick, Cho Hyung Joon, Taejoon Kwon [Aging Cell   21, 9(2022) ]

GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base

Jang Dong Gil, Kwon Keun Yeong, Kweon Yeong Cheon, Byung-gyu Kim, Kyungjae Myung, Lee Hyun-Shik, Park Chan Young, Taejoon Kwon, Tae Joo Park [ELIFE   11(2022) ]

Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair

Mihyun Kim, Hyun Suk Kim, D’Souza Areetha, Gallagher Kaitlyn, Eunwoo Jeong, Topolska-Woś Agnieszka, Ogorodnik Le Meur Kateryna, Tsai Chi-Lin, Tsai Miaw-Sheue, Kee Minyong, Tainer John A., Jung-Eun Yeo, Chazin Walter J., Orlando D. Scharer [Proceedings of the National Academy of Sciences of the United States of America   119, 34(2022) ]

XPC-PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair

Blessing Charlotte, Apelt Katja, van den Heuvel Diana, Gonzalez-Leal Claudia, Rother Magdalena B., van der Woude Melanie, Gonzalez-Prieto Roman, Yifrach Adi, Parnas Avital, Shah Rashmi G., Kuo Tia Tyrsett, Boer Daphne E. C., Cai Jin, Kragten Angela, Hyun-Suk Kim, Orlando D. Scharer, Vertegaal Alfred C. O., Shah Girish M., Adar Sheera, Lans Hannes, van Attikum Haico, Ladurner Andreas G., Luijsterburg Martijn S. [Nature Communications   13, 1(2022) ]

Noncanonical PDK4 action alters mitochondrial dynamics to affect the cellular respiratory status

Thoudam Themis, Chanda Dipanjan, Sinam Ibotombi Singh, Byung-Gyu Kim, Kim Mi-Jin, Oh Chang Joo, Lee Jung Yi, Kim Min-Ji, Park Soo Yeun, Lee Shin Yup, Jung Min-Kyo, Mun Ji Young, Harris Robert A., Ishihara Naotada, Jeon Jae-Han, Lee In-Kyu [Proceedings of the National Academy of Sciences of the United States of America   119, 34(2022) ]

PWWP2B promotes DNA end resection and homologous recombination

Ju Min Kyung, Lee Joo Rak, Choi Yeonsong, Park Seon Young, Sul Hee Jung, Chung Hee Jin, An Soyeong, Lee Semin, Jung Eunyoung, Kim Bohyun, Choi Bo Youn, Kim Bum Jun, Kim Hyeong Su, Lim Hyun, Kang Ho Suk, Soh Jae Seung, Kyungjae Myung, Kim Kab Choong, Cho Ji Woong, Seo Jinwon, Tae Moon Kim, Ja Yil Lee, Kim Yonghwan, Hongtae Kim, Zang Dae Young [EMBO Reports   23, 7(2022) ]

Transcriptional Perturbations of 2,6-Diaminopurine and 2-Aminopurine

Tan Ying, You Changjun, Jiyeong Park, Hyun Suk Kim, Guo Su, Orlando D. Scharer, Wang Yinsheng [ACS Chemical Biology   17, 7, 1672-1676(2022) ]