Korea VirusResearch Institute

IFNL3-adjuvanted HCV DNA vaccine reduces regulatory T cell frequency and increases virus-specific T cell responses

Ji Won Han, Pil Soo Sung, Seon-Hui Hong, Hoyoung Lee, June Young Koh, Hyojin Lee, Scott White, Joel N Maslow, David B Weiner, Su-Hyung Park, Moonsup Jeong, Jeong Heo*, Sang Hoon Ahn*, Eui-Cheol Shin* [JOURNAL OF HEPATOLOGY 73:1, 72-83(2020)]

Chronic hepatitis C, DNA vaccine, IFNL3, Regulatory T cell, T cells

Synovial fluid CD69(+)CD8(+)T cells with tissue-resident phenotype mediate perforin-dependent citrullination in rheumatoid arthritis

Jaehyung Jung, Jung Sun Lee, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo, Eui-Cheol Shin*, Seokchan Hong* [Synovial fluid CD69(+)CD8(+)T cells with tissue-resident phenotype mediate perforin-dependent citrullination in rheumatoid arthritis 9:6(2020)]

ACPA, CD8+ T cells, citrullination, rheumatoid arthritis, tissue‐resident memory T cells

Reactive Polymer Targeting dsRNA as Universal Virus Detection Platform with Enhanced Sensitivity

Jayoung Ku, Sura Kim, Jaemin Park, Tae-Shin Kim, Raisa Kharbash, Eui-Cheol Shin, Kookheon Char, Yoosik Kim*, Sheng Li* [BIOMACROMOLECULES 21:6, 2440-2454(2020)]

Biopolymers, Genetics, Immunology, Infectious diseases

Functions of human liver CD69(+)CD103(-)CD8(+) T cells depend on HIF-2 alpha activity in healthy and pathologic livers

Jong Hoon Kim, Ji Won Han, Young Joon Choi, Min-Seok Rha, June Young Koh, Kyung Hwan Kim, Chang Gon Kim, Yong Joon Lee, A Reum Kim, Junsik Park, Hong Kwan Kim, Byung Soh Min, Seong Il Seo, Minyong Kang, Hye Jung Park, Dai Hoon Han, Soon Il Kim, Myoung Soo Kim, Jae Geun Lee, Dong Hyeon Lee, Won Kim, Jun Yong Park, Su-Hyung Park*, Dong Jin Joo*, Eui-Cheol Shin* [JOURNAL OF HEPATOLOGY 72:6, 1170-1181(2020)]

CD69(+)CD103(-)CD8(+) T cell, HIF-2α, Human liver, Terminal differentiation, Tissue residency

Baseline Serum Interleukin-6 Levels Predict the Response of Patients with Advanced Non-small Cell Lung Cancer to PD-1/PD-L1 Inhibitors

Da Hyun Kang, Cheol-Kyu Park, Chaeuk Chung, In-Jae Oh, Young-Chul Kim, Dongil Park, Jinhyun Kim, Gye Cheol Kwon, Insun Kwon, Pureum Sun, Eui-Cheol Shin, Jeong Eun Lee* [IMMUNE NETWORK 20:3(2020)]

IL-6, Immunological antineoplastic agents, Lung cancer, PD-1/PD-L1

Antiviral Efficacies of FDA-Approved Drugs against SARS-CoV-2 Infection in Ferrets

Su-Jin Park, Kwang-Min Yu, Young-Il Kim, Se-Mi Kim, Eun-Ha Kim, Seong-Gyu Kim, Eun Ji Kim, Mark Anthony B Casel, Rare Rollon, Seung-Gyu Jang, Min-Hyeok Lee, Jae-Hyung Chang, Min-Suk Song, Hye Won Jeong, Younho Choi, Weiqiang Chen, Woo-Jin Shin, Jae U Jung*, Young Ki Choi* [MBIO 11:3(2020)]

COVID-19, antiviral therapeutics, ferrets, immunosuppression, serum neutralization, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Superantigen-related T(H)2 CD4(+) T cells in nonasthmatic chronic rhinosinusitis with nasal polyps

Minyoung Lee, Ho Seon Park, Min Yeong Choi, Hak Zoo Kim, Sung Jin Moon, Ji Yoon Ha, ARim Choi, Young Woo Park, Jong Suk Park, Dae Woo Kim*, Eui-Cheol Shin*, Chul Woo Ahn, Shinae Kang [JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 145:5, 1378-(2020)]

albumin-to-creatinine ratio, biomarker, diabetic nephropathy, estimated glomerular filtration rate, sCD93

Significance of Soluble CD93 in Type 2 Diabetes as a Biomarker for Diabetic Nephropathy: Integrated Results from Human and Rodent Studies

Minyoung Lee, Ho Seon Park, Min Yeong Choi, Hak Zoo Kim, Sung Jin Moon, Ji Yoon Ha, ARim Choi, Young Woo Park, Jong Suk Park, Eui-Cheol Shin, Chul Woo Ahn, Shinae Kang* [JOURNAL OF CLINICAL MEDICINE , 9:5-(2020)]

albumin-to-creatinine ratio, biomarker, diabetic nephropathy, estimated glomerular filtration rate, sCD93