Center for
Genomic Integrity

A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair

van den Heuvel D., Mihyun Kim, Wondergem A.P., van der Meer P.J., Witkamp M., Lambregtse F., Hyun-Suk Kim, Kan F., Apelt K., Kragten A., González-Prieto R., Vertegaal A.C.O., Jung-Eun Yeo, Byung-Gyu Kim, van Doorn R., Orlando D. Schärer, Luijsterburg M.S. [Proceedings of the National Academy of Sciences of the United States of America   120, 11(2023) ]

Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch

Hiroshi Yuita, Isaac F. López-Moyado, Hyeongmin Jeong, Arthur Xiuyuan Cheng, James Scott-Browne, Jungeun An, Toshinori Nakayama, Atsushi Onodera, Myunggon Ko, Anjana Rao [Proceedings of the National Academy of Sciences of the United States of America   120, 6(2023) ]

Ckb and Ybx2 interact with Ribc2 and are necessary for the ciliary beating of multi-cilia

Kwon Keun Yeong, Jeong Hyeongsun, Jang Dong Gil, Taejoon Kwon, Tae Joo Park [Genes & Genomics   45, 2, 157-167(2023) ]

ZNF212 promotes genomic integrity through direct interaction with TRAIP

Chung Hee Jin, Lee Joo Rak, Tae Moon Kim, Kim Soomi, Park Kibeom, Kim Myung-Jin, Jung Eunyoung, Kim Subin, Eun A. Lee, Jae Sun Rae, Sunyoung Hwang, Lee Ja Yil, Orlando D. Scharer, Kim Yonghwan, Kyungjae Myung, Hongtae Kim [Nucleic Acids Research   51, 2, 631-649(2023) ]

Epigenetic Modification of Cytosines in Hematopoietic Differentiation and Malignant Transformation

An Jungeun, Myunggon Ko [International Journal of Molecular Sciences   24, 2(2023) ]

TRIP13 Participates in Immediate-Early Sensing of DNA Strand Breaks and ATM Signaling Amplification through MRE11

Hyeongsun Jeong, Minwoo Wie, In-Joon Baek, Gyuwon Sohn, Si-Hyeon Um, Seon-Gyeong Lee, Yuri Seo, Jaesun Ra, Eun A. Lee, Shinseog Kim, Byung Gyu Kim, Deshpande Rajashree A. A., Paull Tanya T. T., Joo Seok Han, Taejoon Kwon, Kyungjae Myung [CELLS   11, 24(2022) ]

Pyruvate dehydrogenase kinase 4 promotes ubiquitin-proteasome system-dependent muscle atrophy

Sinam Ibotombi Singh, Chanda Dipanjan, Thoudam Themis, Kim Min-Ji, Byung-Gyu Kim, Kang Hyeon-Ji, Lee Jung Yi, Baek Seung-Hoon, Kim Shin-Yoon, Shim Bum Jin, Ryu Dongryeol, Jeon Jae-Han, Lee In-Kyu [Journal of Cachexia Sarcopenia and Muscle   13, 6, 3122-3136(2022) ]

PARP1 recruits DNA translocases to restrain DNA replication and facilitate DNA repair

Ho Yen-Chih, Ku Chen-Syun, Tsai Siang-Sheng, Shiu Jia-Lin, Jiang Yi-Zhen, Miriam Hui Emmanuela, Zhang Han-Wen, Chen Yen-Tzu, Chiu Wen-Tai, Chang Song-Bin, Shen Che-Hung, Kyungjae Myung, Chi Peter, Liaw Hungjiun [PLoS Genetics   18, 12(2022) ]