Center for
Genomic Integrity

TRIP13 Participates in Immediate-Early Sensing of DNA Strand Breaks and ATM Signaling Amplification through MRE11

Hyeongsun Jeong, Minwoo Wie, In-Joon Baek, Gyuwon Sohn, Si-Hyeon Um, Seon-Gyeong Lee, Yuri Seo, Jaesun Ra, Eun A. Lee, Shinseog Kim, Byung Gyu Kim, Deshpande Rajashree A. A., Paull Tanya T. T., Joo Seok Han, Taejoon Kwon, Kyungjae Myung [CELLS   11, 24(2022) ]

Pyruvate dehydrogenase kinase 4 promotes ubiquitin-proteasome system-dependent muscle atrophy

Sinam Ibotombi Singh, Chanda Dipanjan, Thoudam Themis, Kim Min-Ji, Byung-Gyu Kim, Kang Hyeon-Ji, Lee Jung Yi, Baek Seung-Hoon, Kim Shin-Yoon, Shim Bum Jin, Ryu Dongryeol, Jeon Jae-Han, Lee In-Kyu [Journal of Cachexia Sarcopenia and Muscle   13, 6, 3122-3136(2022) ]

PARP1 recruits DNA translocases to restrain DNA replication and facilitate DNA repair

Ho Yen-Chih, Ku Chen-Syun, Tsai Siang-Sheng, Shiu Jia-Lin, Jiang Yi-Zhen, Miriam Hui Emmanuela, Zhang Han-Wen, Chen Yen-Tzu, Chiu Wen-Tai, Chang Song-Bin, Shen Che-Hung, Kyungjae Myung, Chi Peter, Liaw Hungjiun [PLoS Genetics   18, 12(2022) ]

Recent Advances in DNA Lesion Mapping and Repair Mechanisms

Arnold S. Groehler Ⅳ, Kellum A.H. [Chemical Research in Toxicology   36, 1, 5-7(2022) ]

Polycarcin V induces DNA damage response and enables the profiling of DNA-binding proteins

Yue Zongwei, Wu Fan, Guo Fusheng, Jiyeong Park, Wang Jin, Zhang Liyun, Liao Daohong, Li Wenyang, Orlando D. Scharer, Lei Xiaoguang [National Science Review   9, 11(2022) ]

Reciprocal interactions among Cobll1, PACSIN2, and SH3BP1 regulate drug resistance in chronic myeloid leukemia

Park Kibeom, Yoo Hee-Seop, Chang-Kyu Oh, Lee Joo Rak, Chung Hee Jin, Kim Ha-Neul, Kim Soo-Hyun, Kee Kyung-Mi, Kim Tong Yoon, Kim Myungshin, Byung-Gyu Kim, Jae Sun Ra, Kyungjae Myung, Hongtae Kim, Han Seung Hun, Seo Min-Duk, Yoonsung Lee, Kim Dong-Wook [Cancer Medicine   11, 212, 4005-4020(2022) ]

Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1

Chung Scisung, Mi-Sun Kang, Alimbetov Dauren S., Mun Gil-Im, Yunn Na-Oh, Kim Yunjin, Byung-Gyu Kim, Minwoo Wie, Eun A. Lee, Jae Sun Ra, Oh Jung-Min, Lee Donghyun, Lee Keondo, Kim Jihan, Han Seung Hyun, Kim Kyong-Tai, Chung Wan Kyun, Nam Ki Hyun, Park Jaehyun, Lee ByungHoon, Kim Sunghoon, Zhao Weixing, Ryu Sung Ho, Lee Yun-Sil, Kyungjae Myung, Cho Yunje [Nature Communications   13, 1(2022) ]

Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution

Nicole M. Sodir, Luca Pellegrinet, Roderik M. Kortlever, Tania Campos, Yong-Won Kwon, Shinseog Kim, Daniel Garcia, Alessandra Perfetto, Panayiotis Anastasiou, Lamorna Brown Swigart, Mark J. Arends, Trevor D. Littlewood, Gerard I. Evan [Nature Communications   13, 1(2022) ]