Korea VirusResearch Institute

hIL-7-hyFc, A Long-Acting IL-7, Increased Absolute Lymphocyte Count in Healthy Subjects

Sang Won Lee, Donghoon Choi, MinKyu Heo, Eui-Cheol Shin, Su-Hyung Park, So Jeong Kim, Yeon-Kyung Oh, Byung Ha Lee, Se Hwan Yang, Young Chul Sung, Howard Lee* [Clinical and Translational Science 13:6, 1161-1169(2020)]

hIL-7-hyFc

Development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) thermal inactivation method with preservation of diagnostic sensitivity

Young-Il Kim, Mark Anthony B Casel, Se-Mi Kim, Seong-Gyu Kim, Su-Jin Park, Eun-Ha Kim, Hye Won Jeong, Haryoung Poo, Young Ki Choi* [JOURNAL OF MICROBIOLOGY 58:10, 886-891(2020)]

COVID-19, RT-PCR, SARS-CoV-2, genomic stability, heat inactivation

The type I interferon response in COVID-19: implications for treatment

Jeong Seok Lee, Eui-Cheol Shin* [NATURE REVIEWS IMMUNOLOGY 20:10, 585-586(2020)]

Interferons, Viral infection, COVID-19

Peptide Nucleic Acid (PNA)-Enhanced Specificity of a Dual-Target Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR) Assay for the Detection and Differentiation of SARS-CoV-2 from Related Viruses

Won-Suk Choi, Ju Hwan Jeong, Halcyon Dawn G Nicolas, Sol Oh, Khristine Joy C Antigua, Ji-Hyun Park, Beomkyu Kim, Sun-Woo Yoon, Kyeong Seob Shin, Young Ki Choi, Yun Hee Baek*, Min-Suk Song* [DIAGNOSTICS 10:10(2020)]

PNA, RT-qPCR, SARS related-CoV, SARS-CoV-2, dual-target detection

Human liver CD8(+) MAIT cells exert TCR/MR1-independent innate-like cytotoxicity in response to IL-15

Min-Seok Rha, Ji Won Han, Jong Hoon Kim, June-Young Koh, Hye Jung Park, Soon Il Kim, Myoung Soo Kim, Jae Geun Lee, Hyun Woong Lee, Dong Hyeon Lee, Won Kim, Jun Yong Park, Dong Jin Joo*, Su-Hyung Park*, Eui-Cheol Shin* [JOURNAL OF HEPATOLOGY 73:3, 640-650(2020)]

Cytotoxicity, Hepatitis, IL-15, Mucosal-associated invariant T cells, Virus

Distinct tumor immune microenvironments in primary and metastatic lesions in gastric cancer patients

Seung-Myoung Son, Chang Gok Woo, Dae Hoon Kim, Hyo Yung Yun, Hongsik Kim, Hee Kyung Kim, Yaewon Yang, Jihyun Kwon, Minsuk Kwon, Tae-Yong Kim, Hyung-Don Kim, June-Young Koh, Su-Hyung Park, Eui-Cheol Shin*, Hye Sook Han* [SCIENTIFIC REPORTS 10:1(2020)]

Cancer, Immunology, Oncology

Effects of Cryopreservation and Thawing on Single-Cell Transcriptomes of Human T Cells

Jeong Seok Lee, Kijong Yi, Young Seok Ju, Eui-Cheol Shin* [IMMUNE NETWORK 20:4(2020)]

Cryopreservation, Single-cell analysis, T-lymphocytes, regulatory, Transcriptome

Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells

Minji Lee, Eunmin Lee, Seong Kyu Han, Yoon Ha Choi, Dong-Il Kwon, Hyobeen Choi, Kwanghwan Lee, Eun Seo Park, Min-Seok Rha, Dong Jin Joo, Eui-Cheol Shin, Sanguk Kim*, Jong Kyoung Kim*, You Jeong Lee* [NATURE COMMUNICATIONS 11:1(2020)]

Gammadelta T cells, Innate lymphoid cells, NKT cells, Thymus