Korea VirusResearch Institute

Co-blockade of TGFβ and PD-1 Reinvigorates Glioblastoma-Infiltrating CD8+ T Cells That Characteristically Upregulate TGFβRI Expression

A-Reum Kim; Seung Hyuck Jeon; Junsik Park; Eui-Soon Kim; Minsuk Kwon; Jihwan Yoo; Seok-Gu Kang; Su-Hyung Park; Jong Hee ChangCorresponding Author; Eui-Cheol Shin [Clinical Cancer Research 31(15)(2025)]

Pattern recognition receptors and inflammasome: Now and beyond

SuHyeon Oh, Young Ki Choi, SangJoon Lee [Molecules and Cells 48(8)(2025)]

mmune response; Inflammasome; Inflammatory cell death; Innate immunity; Pattern recognition receptor.

Mini bat organs reveal hidden viral threats

Hyunjoon Kim, Bon-Kyoung Koo, Young Ki Choi [Clinical and Translational Medicine 15(8)(2025)]

Targeting innate immune sensors for therapeutic strategies in infectious diseases

Seyun Shin, Young Ki Choi, SangJoon Lee [Journal of Microbiology 63(6)(2025)]

cell death; infection; inflammation; innate immunity; pathogen.

Diverse bat organoids provide pathophysiological models for zoonotic viruses

Hyunjoon Kim #, Seo-Young Heo#, Young-Il Kim#, Dongbin Park, Monford Paul Abishek N, Suhee Hwang, Yong-Ki Lee, Hobin Jang, Jae-Woo Ahn, Jeongmin Ha, Sujin Park, Ho Young Ji, Semi Kim, Isaac Choi, Woohyun Kwon, Jaemoo Kim, Kanghee Kim, Juryeon Gil, Boyeong Jeong, Josea Carmel D Lazarte, Rare Rollon, Jeong Ho Choi, Eun Ha Kim, Seung-Gyu Jang, Hye Kwon Kim, Bo-Young Jeon, Ghazi Kayali, Richard J Webby, Bon-Kyoung Koo, Young Ki Choi [Science Vol. 388, No. 6748, 756-762(2025)]

Patients With Mild COVID-19 Exhibit Low Functional Avidity of SARS-CoV-2 Membrane Protein-Reactive CD4+T Cells

A-Reum Kim; Koh, June-Young; Rha, Min-Seok; Jung, Jae Hyung; Ko, Jae-Hoon; Choi, Hee Kyoung; Jeon, Ji Hoon; Seok, Hyeri; Park, Dae Won; Peck, Kyong Ran; Choi, Jun Yong; Park, Su-Hyung; Choi, Won Suk; Jeong, Hye Won; Eui-Cheol Shin [Immune Network 25(2)(2025)]

COVID-19, SARS-CoV-2, CD4-positive-T-lymphocytes, Cross-reactivity; Functional avidity

Redefining the immune landscape of hepatitis A virus infection

Colasanti, Ombretta; Yu, Hosun; Lohmann, Volker; Eui-Cheol Shin [Experimental & Molecular Medicine 51(2025)]

Investigating Human Liver Tissue-Resident Memory T Cells from the Perspectives of Gastroenterologists and Hepatologists

Han, Ji Won; Eui-Cheol Shin [Gut and Liver 19(2), 161-170(2025)]

T-lymphocytes, Tissue resident T cell, Liver diseases