IBS Life Science Institute

NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs

Van Haute L, Lee SY, McCann BJ, Powell CA, Bansal D, Vasiliauskaitė L, Garone C, Shin S, Kim JS, Frye M, Gleeson JG, Miska EA, Rhee HW, Minczuk M [Nucleic Acids Research 47(16), 8720-8733(September, 2019)]

Tankyrase inhibition preserves osteoarthritic cartilage by coordinating cartilage matrix anabolism via effects on SOX9 PARylation

Sukyeong Kim, Sangbin Han, Yeongjae Kim, Hyeon-Seop Kim, Young-Ran Gu, Donghyun Kang, Yongsik Cho, Hyeonkyeong Kim, Jeeyeon Lee, Yeyoung Seo, Moon Jong Chang, Chong Bum Chang, Seung-Baik Kang & Jin-Hong Kim [Nature Communications 10(October, 2019)]

Brain somatic mutations in MTOR reveal translational dysregulations underlying intractable focal epilepsy

Jang Keun Kim, Jun Cho, Se Hoon Kim, Hoon-Chul Kang, Dong-Seok Kim, V. Narry Kim, and Jeong Ho Lee [Journal of Clinical Investigation 129(10), 4207-4223(1 October, 2019)]

Stress-activated miR-204 governs senescent phenotypes of chondrocytes to promote osteoarthritis development

Donghyun Kang, Jungkwon Shin, Yongsik Cho, Hyeon-Seop Kim, Young-Ran Gu, Haedong Kim, Kwon Tae You, Moon Jong Chang, Chong Bum Chang, Seung-Baik Kang, Jong-Seo Kim, V. Narry Kim and Jin-Hong Kim [Science Translational Medicine 11(486)(April, 2019)]

Fucoidan-coated coral-like Pt nanoparticles for computed tomography-guided highly enhanced synergistic anticancer effect against drug-resistant breast cancer cells

Seounghun Kang, Kyunglee Kang, Ari Chae, Young-Kwan Kim, Hongje Jang and Dal-Hee Min [Nanoscale 11(32), 15173-15183(August, 2019)]

Direct Monitoring of Cancer-Associated mRNAs in Living Cells to Evaluate the Therapeutic RNAi Efficiency Using Fluorescent Nanosensor

Seong Min Ahn, Seounghun Kang, Dal-Hee Min [ACS Sensors 4(5), 1174-1179(May, 2019)]

SERPINA3 is a key modulator of HNRNP-K transcriptional activity against oxidative stress in HCC

Eunkyong Ko, Jong-Seo Kim, Jong Woo Bae, Jeesoo Kim, Sung-Gyoo Park, Guhung Jung [Redox Biology 24(June, 2019)]

Hydrothermal Galvanic-Replacement-Tethered Synthesis of Ir–Ag–IrO2 Nanoplates for Computed Tomography-Guided Multiwavelength Potent Thermodynamic Cancer Therapy

Gyeonghye Yim, Seounghun Kang, Young-Jin Kim, Young-Kwan Kim, Dal-Hee Min, and Hongje Jang [ACS Nano 13(3), 3434-3447(26 March, 2019)]