Korea VirusResearch Institute

Peptide Nucleic Acid (PNA)-Enhanced Specificity of a Dual-Target Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR) Assay for the Detection and Differentiation of SARS-CoV-2 from Related Viruses

Won-Suk Choi, Ju Hwan Jeong, Halcyon Dawn G Nicolas, Sol Oh, Khristine Joy C Antigua, Ji-Hyun Park, Beomkyu Kim, Sun-Woo Yoon, Kyeong Seob Shin, Young Ki Choi, Yun Hee Baek*, Min-Suk Song* [DIAGNOSTICS 10:10(2020)]

PNA, RT-qPCR, SARS related-CoV, SARS-CoV-2, dual-target detection

Antiviral Efficacies of FDA-Approved Drugs against SARS-CoV-2 Infection in Ferrets

Su-Jin Park, Kwang-Min Yu, Young-Il Kim, Se-Mi Kim, Eun-Ha Kim, Seong-Gyu Kim, Eun Ji Kim, Mark Anthony B Casel, Rare Rollon, Seung-Gyu Jang, Min-Hyeok Lee, Jae-Hyung Chang, Min-Suk Song, Hye Won Jeong, Younho Choi, Weiqiang Chen, Woo-Jin Shin, Jae U Jung*, Young Ki Choi* [MBIO 11:3(2020)]

COVID-19, antiviral therapeutics, ferrets, immunosuppression, serum neutralization, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Infection and Rapid Transmission of SARS-CoV-2 in Ferrets

Young-Il Kim, Seong-Gyu Kim, Se-Mi Kim, Eun-Ha Kim, Su-Jin Park, Kwang-Min Yu, Jae-Hyung Chang, Eun Ji Kim, Seunghun Lee, Mark Anthony B Casel, Jihye Um, Min-Suk Song, Hye Won Jeong, Van Dam Lai, Yeonjae Kim, Bum Sik Chin, Jun-Sun Park, Ki-Hyun Chung, Suan-Sin Foo, Haryoung Poo, In-Pil Mo, Ok-Jun Lee, Richard J Webby, Jae U Jung*, Young Ki Choi* [Cell Host and Microbe 27:5, 704-(2020)]

2019-nCoV, 2019-novel coronavirus, COVID-19, SARS-CoV-2, ferrets, novel coronavirus disease, severe acute respiratory syndrome coronavirus 2, transmission, virus shedding

Genetic and pathogenic diversity of severe fever with thrombocytopenia syndrome virus SFTSV in South Korea

Seok-Min Yun, Su-Jin Park, Young-Il Kim, Sun-Whan Park, Min-Ah Yu, Hyeok-Il Kwon, Eun-Ha Kim, Kwang-Min Yu, Hye Won Jeong, Jungsang Ryou, Won-Ja Lee, Youngmee Jee, Joo-Yeon Lee*, Young Ki Choi* [JCI INSIGHT 5:2(2020)]

Infectious disease, Platelets, Virology

Cross-genotype protection of live-attenuated vaccine candidate for severe fever with thrombocytopenia syndrome virus in a ferret model

Kwang-Min Yu, Su-Jin Park, Min-Ah Yu, Young-Il Kim, Younho Choi, Jae U Jung, Benjamin Brennan*, Young Ki Choi* [PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116:52, 26900-26908(2019)]

SFTS, bunyavirus, emerging banyangvirus, ferret model, live attenuated vaccine

A Novel Neuraminidase-Dependent Hemagglutinin Cleavage Mechanism Enables the Systemic Spread of an H7N6 Avian Influenza Virus

Hyeok-Il Kwon, Young-Il Kim, Su-Jin Park, Eun-Ha Kim, Semi Kim, Young-Jae Si, Min-Suk Song, Philippe Noriel Q Pascua, Elena A Govorkova, Robert G Webster, Richard J Webby*, Young Ki Choi* [MBIO 10:6(2019)]

GRG motif, H7, N6 neuraminidase, influenza, pathogenicity, thrombin-like protease, trypsin-independent growth, virulence

Greater Efficacy of Black Ginseng (CJ EnerG) over Red Ginseng against Lethal Influenza A Virus Infection

Eun-Ha Kim, Son-Woo Kim, Su-Jin Park, Semi Kim, Kwang-Min Yu, Seong Gyu Kim, Seung Hun Lee, Yong-Ki Seo, Nam-Hoon Cho, Kimoon Kang, Do Y Soung*, Young-Ki Choi* [NUTRIENTS 11:8(2019)]

antiviral, black ginseng, cytokines, influenza A virus, oral administration

Development of a SFTSV DNA vaccine that confers complete protection against lethal infection in ferrets

Jeong-Eun Kwak, Young-Il Kim, Su-Jin Park, Min-Ah Yu, Hyeok-Il Kwon, Sukyeong Eo, Tae-Shin Kim, Joon Seok, Won-Suk Choi, Ju Hwan Jeong, Hyojin Lee, Youngran Cho, Jin Ah Kwon, Moonsup Jeong, Joel N Maslow, Yong-Eun Kim, Haili Jeon, Kee K Kim, Eui-Cheol Shin, Min-Suk Song, Jae U Jung, Young Ki Choi*, Su-Hyung Park* [NATURE COMMUNICATIONS 10:1(2019)]

DNA vaccines, Viral infection