Korea VirusResearch Institute

Infection Route Impacts the Pathogenesis of Severe Fever with Thrombocytopenia Syndrome Virus in Ferrets

Su-Jin Park*, Young-Il Kim, Mark Anthony Casel, Eun-Ha Kim, Se-Mi Kim, Kwang-Min Yu, Rare Rollon, Seung-Gyu Jang, Hye Won Jeong, Young Ki Choi* [Viruses 14:6(2022)]

SFTSV, aged ferret, animal model, infection routes

Methods for fighting emerging pathogens

Luiz Carlos Junior Alcantara, Lucas Amenga-Etego, Robin Andersson, Moumita Bhaumik, Young Ki Choi, Hélène Decaluwe, Jemma Geoghegan, Bart L Haagmans, Susana López, Maowia M Mukhtar, Erni Nelwan, Elias A Rahal, Kei Sato, Ella H Sklan, Yvonne Su Chuan Fang [Nature methods 19:4, 395-397(2022)]

research methods, emerging pathogens

Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8

Xin Wu, Tian Xia, Woo-Jin Shin, Kwang-Min Yu, Wooram Jung, Alexandra Herrmann, Suan-Sin Foo, Weiqiang Chen, Pengfei Zhang, Jong-Soo Lee, Haryoung Poo, Suzy A A Comhair, Lara Jehi, Young Ki Choi, Armin Ensser, Jae U Jung* [mBio 13:2(2022)]

COVID-19, inflammation, viral IL-17

Multiple HA substitutions in highly pathogenic avian influenza H5Nx viruses contributed to the change in the NA subtype preference

Khristine Joy C. Antigua,Yun Hee Baek, Won-Suk Choi, Ju Hwan Jeong, Eun-Ha Kim, Sol Oh, Sun-Woo Yoon, Changil Kim, Eung-Gook Kim, So-Young Choi, Seung Kon Hong, Young Ki Choi*, Min Suk Song* [Virulence 13:1, 990-1004(2022)]

Avian influenza, clade 2.3.4, H5Nx, antigenic drift, antigenic shift, functional balance

Age-dependent pathogenic characteristics of SARS-CoV-2 infection in ferrets

Young-Il Kim, Kwang-Min Yu, June-Young Koh, Eun-Ha Kim, Se-Mi Kim, Eun Ji Kim, Mark Anthony Casel, Rare Rollon, Seung-Gyu Jang, Min-Suk Song, Su-Jin Park, Hye Won Jeong, Eung-Gook Kim, Ok-Jun Lee, Younho Choi, Shin-Ae Lee, Su-Hyung Park, Jae U Jung*, Young Ki Choi* [Nature Communications 13:21(2022)]

COVID-19, age-dependent, ferrets, pathogenesis, clinical manifestations

Coinfection with SARS-CoV-2 and Influenza A Virus Increases Disease Severity and Impairs Neutralizing Antibody and CD4+ T Cell Responses

Eun-Ha Kim, Thi-Quyen Nguyen, Mark Anthony B Casel, Rare Rollon, Se-Mi Kim, Young-Il Kim, Kwang-Min Yu, Seung-Gyu Jang, Jihyun Yang, Haryoung Poo, Jae U Jung, Young Ki Choi* [Journal of Virology 96:6(2022)]

SARS-CoV-2, T cell, bronchoalveolar lavage fluid, chemokine, coinfection, cytokine, hACE2 mice, immune response, influenza A virus, neutralizing antibody

Transmissibility and pathogenicity of SARS-CoV-2 variants in animal models

Young-Il Kim, Mark Anthony B Casel, Young Ki Choi* [Journal of microbiology (Seoul, Korea) 60:3, 255-267(2022)]

SARS-CoV-2, animal models, pathogenicity, transmissibility, variants

Critical role of neutralizing antibody for SARS-CoV-2 reinfection and transmission

Young-Il Kim, Se-Mi Kim, Su-Jin Park, Eun-Ha Kim, Kwang-Min Yu, Jae-Hyung Chang, Eun Ji Kim, Mark Anthony B Casel, Rare Rollon, Seung-Gyu Jang, Jihye Um, Min-Suk Song, Hye Won Jeong, Eung-Gook Kim, Yeonjae Kim, So Yeon Kim, Jun-Sun Park, Mi Sun Park, Geun-Yong Kwon, Sang Gu Yeo, Shin-Ae Lee, Youn Jung Choi, Jae U Jung, Young Ki Choi* [Emerging Microbes and Infections 10:1, 152-160(2021)]

COVID-19, SARS-CoV-2, ferret model, neutralizing antibody, reinfection