%PDF-1.6
%
261 0 obj
<>>>
endobj
260 0 obj
<>stream
application/pdf
Science Journals — AAAS
2019-03-15T18:30:27+08:00
2019-10-30T01:14:12-07:00
2019-10-30T01:14:12-07:00
Adobe InDesign CC 2017 (Windows)
uuid:e8728223-1dd1-11b2-0a00-af00288b85ff
xmp.did:f4fd3488-9b3f-9d45-a5a3-8a4b2d55f952
xmp.id:354f560c-0503-9e44-907c-62eea2aa5ae0
proof:pdf
xmp.iid:43d959c8-7a83-5046-8f0b-4ce6fea00df6
xmp.did:3c1a44db-b4cf-7e40-805f-12478d22c8a0
xmp.did:f4fd3488-9b3f-9d45-a5a3-8a4b2d55f952
default
converted
from application/x-indesign to application/pdf
Adobe InDesign CC 2017 (Windows)
/
2019-03-15T18:30:27+08:00
Adobe PDF Library 15.0
False
endstream
endobj
256 0 obj
<>
endobj
258 0 obj
<>
endobj
13 0 obj
<>
endobj
158 0 obj
<>
endobj
124 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageC/ImageI]/Properties<>/XObject<>>>/Rotate 0/Thumb 125 0 R/TrimBox[0.0 0.0 594.0 756.0]/Type/Page>>
endobj
169 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageC/ImageI]/Properties<>/XObject<>>>/Rotate 0/Thumb 170 0 R/TrimBox[0.0 0.0 594.0 756.0]/Type/Page>>
endobj
195 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/Thumb 196 0 R/TrimBox[0.0 0.0 594.0 756.0]/Type/Page>>
endobj
198 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/Thumb 199 0 R/TrimBox[0.0 0.0 594.0 756.0]/Type/Page>>
endobj
205 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/Thumb 206 0 R/TrimBox[0.0 0.0 594.0 756.0]/Type/Page>>
endobj
215 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/Thumb 216 0 R/TrimBox[0.0 0.0 594.0 756.0]/Type/Page>>
endobj
227 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/Thumb 228 0 R/TrimBox[0.0 0.0 594.0 756.0]/Type/Page>>
endobj
309 0 obj
<>/ProcSet[/PDF/Text/ImageC]/XObject<>>>/Type/Page>>
endobj
330 0 obj
[335 0 R 336 0 R 337 0 R 338 0 R 339 0 R 340 0 R]
endobj
331 0 obj
<>stream
q
174.25 0 0 21.75 72 662.25 cm
/Im0 Do
Q
BT
/T1_0 1 Tf
10 0 0 10 72 611.99997 Tm
(inhibitors in Alzheimer's disease)Tj
0 1 TD
(Newly developed reversible MAO-B inhibitor circumvents the shortcomings \
of irreversible)Tj
ET
BT
/T1_1 1 Tf
8 0 0 8 72 574.99991 Tm
(Cho, Ae Nim Pae, C. Justin Lee and Ki Duk Park)Tj
T*
(Londhe, Jina Kim, Sung Jin Cho, Suengmok Cho, Changho Lee, Sung Yeoun Hw\
ang, Sang Wook Kim, Soo-Jin Oh, Jeiwon)Tj
0 1.00001 TD
(Jeong Shin, Oleg Yarishkin, Seonmi Jo, Mijeong Park, Seul Ki Yeon, Siwon\
Kim, Jeongyeon Kim, Min-Ho Nam, Ashwini M. )Tj
0 1 TD
(Jong-Hyun Park, Yeon Ha Ju, Ji Won Choi, Hyo Jung Song, Bo Ko Jang, Juns\
ung Woo, Heejung Chun, Hyeon Jeong Kim, Su)Tj
ET
BT
/T1_1 1 Tf
8 0 0 8 72 528.99997 Tm
(DOI: 10.1126/sciadv.aav0316)Tj
4.22401 1 Td
( \(3\), eaav0316.)Tj
/T1_0 1 Tf
-0.556 0 Td
(5)Tj
/T1_2 1 Tf
-3.66801 0 Td
(Sci Adv\240)Tj
ET
BT
/T1_0 1 Tf
6 0 0 6 79 459 Tm
(ARTICLE TOOLS)Tj
ET
BT
0 0 1 rg
/T1_1 1 Tf
8 0 0 8 187 457 Tm
(http://advances.sciencemag.org/content/5/3/eaav0316)Tj
ET
BT
0 g
/T1_0 1 Tf
6 0 0 6 79 416.99997 Tm
(MATERIALS)Tj
0 1.00001 TD
(SUPPLEMENTARY )Tj
ET
BT
0 0 1 rg
/T1_1 1 Tf
8 0 0 8 187 421 Tm
(http://advances.sciencemag.org/content/suppl/2019/03/18/5.3.eaav0316.DC1\
)Tj
ET
BT
0 g
/T1_0 1 Tf
6 0 0 6 79 381 Tm
(REFERENCES)Tj
ET
BT
0 0 1 rg
/T1_1 1 Tf
8 0 0 8 187 370.99997 Tm
(http://advances.sciencemag.org/content/5/3/eaav0316#BIBL)Tj
0 g
0 1 TD
(This article cites 38 articles, 3 of which you can access for free)Tj
ET
BT
/T1_0 1 Tf
6 0 0 6 79 345 Tm
(PERMISSIONS)Tj
ET
BT
0 0 1 rg
/T1_1 1 Tf
8 0 0 8 187 343 Tm
(http://www.sciencemag.org/help/reprints-and-permissions)Tj
ET
BT
/T1_1 1 Tf
8 0 0 8 193.38391 128 Tm
(Terms of Service)Tj
0 g
-15.17299 0 Td
(Use of this article is subject to the )Tj
ET
72 114 m
522 114 l
0 0 m
S
BT
ET
BT
/T1_1 1 Tf
8 0 0 8 72 77.99991 Tm
(registered trademark of AAAS.)Tj
52.63197 1 Td
(is a)Tj
/T1_2 1 Tf
-8.50401 0 Td
(Science Advances )Tj
/T1_1 1 Tf
-44.12796 0 Td
(Association for the Advancement of Science. No claim to original U.S. Go\
vernment Works. The title )Tj
0 1.00001 TD
(York Avenue NW, Washington, DC 20005. 2017 \251 The Authors, some rights\
reserved; exclusive licensee American )Tj
8.50401 1 Td
(\(ISSN 2375-2548\) is published by the American Association for the Adva\
ncement of Science, 1200 New)Tj
/T1_2 1 Tf
-8.50401 0 Td
(Science Advances )Tj
ET
BT
/T1_1 1 Tf
0 -8 8 0 576 325.5401 Tm
( on October 30, 2019)Tj
0 0 1 rg
-14.39598 0 Td
(http://advances.sciencemag.org/)Tj
0 g
-8.11398 0 Td
(Downloaded from )Tj
ET
endstream
endobj
334 0 obj
<>/Filter/FlateDecode/Height 87/Length 38572/Name/X/Subtype/Image/Type/XObject/Width 697>>stream
HXUs0
7PSLMxLE/J[**^F$j5à,uQVYF
"ega3Y=:m{y?BΩoFp:!",0zYCƻ4 Ys.SY:= =CgBz.:p&w 83Z^DHn1^' 88F}-_WzӨ
*K+vnwg ;u%אb\7XX釤[sJzl
8QAUyAڂk*֠#3tB"t4oBFz4sܰS^kYAɰ˜{o$$F
M|{( lT٧nQ]k:Hcl<&-1 C0O:m!/4 ;+l[ OXHO^ C,ҦϱZ"9Zij52*%TV1Fk;?Hsc= {:Gr
P