Korea VirusResearch Institute

Friday, April 1 2022, 2:00pm     

Novel Vaccine Adjuvants Empowered by Coded Signal Integration

Yong Taik LIM, PhD

SKKU Advanced Institute of Nano Technology (SAINT) and Department of Nano Engineering, Sungkyunkwan University (SKKU), Suwon, Gyeonggi-do, South Korea

In this talk, general issues in the development of vaccine adjuvants will be discussed briefly, which followed by the introduction of novel vaccine adjuvants generated by the coded signal integration of innate stimuli. Vaccine adjuvants are compounds that can increase and/or modulate the intrinsic immunogenicity of an antigen. Rationally designed adjuvants can induce potent and persistent immune responses as well as minimize immune-related toxicities. Recently, our research group has developed a novel type of immunostimulatory system which integrated innate stimuli in the context of time, order, and duration. Here, I would like to present the representative immunological characteristics of the newly developed immunostimulatory system and discuss the prospects of it as a next-generation vaccine adjuvant.