Research Fellow
Dr. Doyun Lee majored in Molecular Biology at Seoul National University. During his graduate studies he was trained as an electrophysiologist. By combining patch-clamp recordings and confocal imaging, he investigated calcium dynamics at individual synaptic boutons during synaptic plasticity. After completing his PhD, he joined Dr. Albert Lee’s lab at Janelia Research Campus of Howard Hughes Medical Institute, where he developed whole-cell recording techniques in freely moving rats and mice. He revealed neuronal mechanisms of place cell firing by using the state-of-the-art techniques. Since he joined the center in 2015 as a principal investigator, he has been striving to elucidate neural mechanisms underlying recognition of individual conspecifics by recording activity of a large population of neurons in mice performing social recognition tasks that his lab recently developed.
doyunleelab.org (doyunleelab.wordpress.com)
Ph.D.
Physiology, Seoul National University College of Medicine, Korea (2007)
M.S.
Molecular biology, Seoul National University College of Natural Sciences, Korea (2000)
B.S.
Molecular biology, Seoul National University College of Natural Sciences, Korea (1998)
2020 – present | Research Fellow, Center for Cognition and Sociality, Institute for Basic Science, Korea |
2015 – 2020 | Tenure-Track Research Fellow, Center for Cognition and Sociality, Institute for Basic Science, Korea |
2008 – 2015 | Postdoctoral associate (adviser: Dr. Albert Lee), Howard Hughes Medical Institute / Janelia Research Campus, USA |
2007 – 2008 | Postdoctoral fellow (adviser: Dr. Suk-Ho Lee), National Research Laboratory for Cell Physiology, Department of Physiology, SNU Med. and Neuroscience Research Institute, SNU Medical Research Center, Korea |
2003 – 2003 | Research fellow (advisers: Dr. Suk-Ho Lee & Dr. Won-Kyung Ho), Department of Physiology, Seoul National University College of Medicine, Korea |
* Social information processing and memory formation
* Episodic information processing
* Ensemble perception
Lee J, Bae C, Lee D*, Jung MW* (2020) Transient effect of mossy fiber stimulation on spatial firing of CA3 neurons in familiar and novel environments. Hippocampus, 30(7):693-702
Lee J, Yun M, Cho E, Lee JW, Lee D*, Jung MW* (2019) Transient effect of mossy fiber stimulation on spatial firing of CA3 neurons. Hippocampus, 29(7):639-651
Lee D* and Lee AK* (2017) Whole-cell recording in the awake brain. Cold Spring Harb Protoc doi:10.1101/pdb.top087304
Lee D*, Shtengel G, Osborne JE, Lee AK* (2014) Anesthetized- and awake-patched whole-cell recordings in freely moving rats using UV-cured collar-based electrode stabilization. Nature Protocols, 9:2784-2795.
Lee D*, Lin B, Lee AK*. (2012) Hippocampal Place Fields Emerge upon Single-Cell Manipulation of Excitability During Behavior. Science, 337(6096):849-853
Lee D, Lee KH, Ho WK, Lee SH. (2007) Target cell-specific involvement of presynaptic mitochondria in post-tetanic potentiation at hippocampal mossy fiber synapses. J Neurosci, 27(50):13603-13613
Senior Researcher
yblee85@ibs.re.kr
Postdoctoral Researcher
kong5202@kaist.ac.kr
PhD Student
joowonkim@kaist.ac.kr
PhD Student
jongrok.do@gmail.com